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Literature summary extracted from

  • Hollmann, S.; Touster, O.
    The L-xylulose-xylitol enzyme and other polyol dehydrogenases of guinea pig liver mitochondria (1957), J. Biol. Chem., 225, 87-102.
    View publication on PubMed

General Stability

EC Number General Stability Organism
1.1.1.10 inactivation during dialysis Cavia porcellus

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.10 iodoacetate complete inhibition of L-xylulose reductive activity at 5 mM Cavia porcellus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.1.1.10 Mg2+
-
 Cavia porcellus

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.10 Cavia porcellus
-
 guinea pig
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.10 liver
-
 Cavia porcellus
-

Storage Stability

EC Number Storage Stability Organism
1.1.1.10 2°C, aqueous solution, many weeks Cavia porcellus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.10 L-xylulose + NADPH + H+
-
 Cavia porcellus L-xylitol + NADP+
-
 r
1.1.1.10 xylitol + NADP+
-
 Cavia porcellus L-xylulose + NADPH + H+
-
 r

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
1.1.1.10 50
-
 20 min stable Cavia porcellus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.10 7.5
-
 approximately Cavia porcellus

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
1.1.1.10 4
-
 2°C, 2 h stable Cavia porcellus
1.1.1.10 9
-
 room temperature, several h stable Cavia porcellus

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.10 NAD+ much less effective than NADP+ Cavia porcellus
1.1.1.10 NADP+ much more effective than NAD+ Cavia porcellus