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Literature summary extracted from

  • Juan, E.; Gonzalez-Duarte, R.
    Determination of some biochemical and structural features of alcohol dehydrogenases from Drosophila simulans and Drosophila virilis. Comparison of their properties with the Drosophila melanogaster Adhs enzyme (1981), Biochem. J., 195, 61-69.
    View publication on PubMedView publication on EuropePMC

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.1 0.19
-
 NAD+
-
 Drosophila simulans
1.1.1.1 0.2
-
 NAD+
-
 Drosophila virilis
1.1.1.1 0.26
-
 NAD+
-
 Drosophila melanogaster
1.1.1.1 0.41
-
 butan-2-ol
-
 Drosophila simulans
1.1.1.1 0.86
-
 butan-2-ol
-
 Drosophila melanogaster
1.1.1.1 0.93
-
 propan-2-ol
-
 Drosophila simulans
1.1.1.1 1.6
-
 butan-2-ol
-
 Drosophila virilis
1.1.1.1 1.87
-
 propan-2-ol
-
 Drosophila melanogaster
1.1.1.1 1.99
-
 propan-2-ol
-
 Drosophila virilis
1.1.1.1 3.01
-
 butan-1-ol
-
 Drosophila simulans
1.1.1.1 3.31
-
 butan-1-ol
-
 Drosophila melanogaster
1.1.1.1 3.33
-
 propan-2-ol
-
 Drosophila simulans
1.1.1.1 3.42
-
 propan-2-ol
-
 Drosophila melanogaster
1.1.1.1 4.16
-
 propan-2-ol
-
 Drosophila virilis
1.1.1.1 5.22
-
 ethanol
-
 Drosophila simulans
1.1.1.1 6.44
-
 ethanol
-
 Drosophila virilis
1.1.1.1 8.92
-
 ethanol
-
 Drosophila melanogaster

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.1.1 27800
-
 2 * 27800, SDS-PAGE Drosophila melanogaster
1.1.1.1 27800
-
 2 * 27800, SDS-PAGE Drosophila virilis
1.1.1.1 27800
-
 2 * 27800, SDS-PAGE Drosophila simulans
1.1.1.1 54600
-
 gel filtration Drosophila virilis
1.1.1.1 55600
-
 gel filtration Drosophila melanogaster
1.1.1.1 57600
-
 gel filtration Drosophila simulans

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.1 Drosophila melanogaster
-
-
-
1.1.1.1 Drosophila simulans
-
-
-
1.1.1.1 Drosophila virilis
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.1 butan-2-ol + NAD+
-
 Drosophila melanogaster butan-2-one + NADH
-
 ?
1.1.1.1 butan-2-ol + NAD+
-
 Drosophila virilis butan-2-one + NADH
-
 ?
1.1.1.1 butan-2-ol + NAD+
-
 Drosophila simulans butan-2-one + NADH
-
 ?
1.1.1.1 butanol + NAD+
-
 Drosophila melanogaster butyraldehyde + NADH
-
 ?
1.1.1.1 butanol + NAD+
-
 Drosophila virilis butyraldehyde + NADH
-
 ?
1.1.1.1 butanol + NAD+
-
 Drosophila simulans butyraldehyde + NADH
-
 ?
1.1.1.1 ethanol + NAD+
-
 Drosophila melanogaster acetaldehyde + NADH
-
 ?
1.1.1.1 ethanol + NAD+
-
 Drosophila virilis acetaldehyde + NADH
-
 ?
1.1.1.1 ethanol + NAD+
-
 Drosophila simulans acetaldehyde + NADH
-
 ?
1.1.1.1 propan-2-ol + NAD+
-
 Drosophila melanogaster acetone + NADH
-
 ?
1.1.1.1 propan-2-ol + NAD+
-
 Drosophila virilis acetone + NADH
-
 ?
1.1.1.1 propan-2-ol + NAD+
-
 Drosophila simulans acetone + NADH
-
 ?

Subunits

EC Number Subunits Comment Organism
1.1.1.1 dimer 2 * 27800, SDS-PAGE Drosophila melanogaster
1.1.1.1 dimer 2 * 27800, SDS-PAGE Drosophila virilis
1.1.1.1 dimer 2 * 27800, SDS-PAGE Drosophila simulans

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.1 7.5
-
 and second optimum at pH 9.9 Drosophila simulans
1.1.1.1 8
-
 and a second optimum at pH 9.5 Drosophila melanogaster
1.1.1.1 8
-
 and a second optimum at pH 9.5 Drosophila virilis
1.1.1.1 9.5
-
 and a second optimum at pH 8.0 Drosophila melanogaster
1.1.1.1 9.5
-
 and a second optimum at pH 8.0 Drosophila virilis
1.1.1.1 9.9
-
 and second optimum at pH 7.5 Drosophila simulans

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.1 NAD+
-
 Drosophila melanogaster
1.1.1.1 NAD+
-
 Drosophila virilis
1.1.1.1 NAD+
-
 Drosophila simulans
1.1.1.1 NADH
-
 Drosophila melanogaster
1.1.1.1 NADH
-
 Drosophila virilis
1.1.1.1 NADH
-
 Drosophila simulans