EC Number | Cloned (Comment) | Organism |
---|---|---|
1.14.11.18 | in bacterial expression vector pQE-31 | Homo sapiens |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.14.11.18 | 2-methylhexadecanoyl-CoA | 56% of control activity | Homo sapiens | |
1.14.11.18 | hexadecanoyl-CoA | 74% of control activity | Homo sapiens |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.14.11.18 | Fe2+ | requirement | Homo sapiens | |
1.14.11.18 | Fe2+ | requirement | Rattus norvegicus | |
1.14.11.18 | Mg2+ | - |
Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.11.18 | Homo sapiens | - |
human | - |
1.14.11.18 | Rattus norvegicus | - |
rat | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.14.11.18 | liver | - |
Homo sapiens | - |
1.14.11.18 | liver | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.11.18 | 3-methylhexadecanoyl-CoA + 2-oxoglutarate + O2 | - |
Homo sapiens | 2-hydroxy-3-methylhexadecanoyl-CoA + succinate + CO2 | - |
? | |
1.14.11.18 | 3-methylhexadecanoyl-CoA + 2-oxoglutarate + O2 | - |
Rattus norvegicus | 2-hydroxy-3-methylhexadecanoyl-CoA + succinate + CO2 | - |
? | |
1.14.11.18 | phytanoyl-CoA + 2-oxoglutarate + O2 | - |
Rattus norvegicus | alpha-hydroxyphytanoyl-CoA + succinate + CO2 | - |
? | |
1.14.11.18 | phytanoyl-CoA + 2-oxoglutarate + O2 | no activity with octadecanoyl-CoA, lignoceroyl-CoA, 2-methylhexadecanoyl-CoA and 4,8,12-trimethyltridecanoyl-CoA | Homo sapiens | alpha-hydroxyphytanoyl-CoA + succinate + CO2 | - |
? |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.14.11.18 | ATP | - |
Homo sapiens | |
1.14.11.18 | ATP | - |
Rattus norvegicus | |
1.14.11.18 | GTP | - |
Homo sapiens | |
1.14.11.18 | additional information | UTP, CTP, ITP, AMP, ADP, NAD+ and FAD can not act as cofactors, ATP and GTP can be replaced by adenosine-5'-O-(3-thiotriphosphate), adenylylimidodiphosphate, adenylyl-(beta,gamma-methylene)-diphosphonate and guanylyl-imidodiphosphate | Homo sapiens |