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Literature summary extracted from

  • Hango, T.; Nojima, S.; Setaka, M.
    Purification and characterization of (H+ + K+)-ATPase from hog gastric mucosa (1990), Jpn. J. Pharmacol., 52, 295-305.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.2.2.19 (CH3)4N+
-
Sus scrofa
7.2.2.19 Ba2+
-
Sus scrofa
7.2.2.19 Ca2+
-
Sus scrofa
7.2.2.19 Cd2+
-
Sus scrofa
7.2.2.19 Cu2+
-
Sus scrofa
7.2.2.19 Li+
-
Sus scrofa
7.2.2.19 N,N'-dicyclohexylcarbodiimide
-
Sus scrofa
7.2.2.19 Na+
-
Sus scrofa
7.2.2.19 Omeprazole pH-dependent inhibition Sus scrofa
7.2.2.19 p-chloromercuribenzene sulfonate
-
Sus scrofa
7.2.2.19 Sr2+
-
Sus scrofa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.2.2.19 membrane
-
Sus scrofa 16020
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
7.2.2.19 K+ stimulates , maximal activity at 5 mM Sus scrofa
7.2.2.19 NH4+ stimulates, maximal activity at 20 mM Sus scrofa
7.2.2.19 Rb+ stimulates Sus scrofa
7.2.2.19 Tl+ stimulates Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
7.2.2.19 Sus scrofa
-
hog
-

Purification (Commentary)

EC Number Purification (Comment) Organism
7.2.2.19
-
Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
7.2.2.19 stomach gastric mucosa Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.2.2.19 2'-deoxyATP + H2O + H+/in + K+/out 37% of the activity with ATP Sus scrofa 2'-deoxyADP + phosphate + H+/out + K+/in
-
?
7.2.2.19 ADP + H2O + H+/in + K+/out 7.5% of the activity with ATP Sus scrofa AMP + phosphate + H+/out + K+/in
-
?
7.2.2.19 ATP + H2O + H+/in + K+/out
-
Sus scrofa ADP + phosphate + H+/out + K+/in
-
?
7.2.2.19 CTP + H2O + H+/in + K+/out 13.2% of the activity with ATP Sus scrofa CDP + phosphate + H+/out + K+/in
-
?

Subunits

EC Number Subunits Comment Organism
7.2.2.19 ?
-
Sus scrofa

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
7.2.2.19 7.4
-
-
Sus scrofa

pH Range

EC Number pH Minimum pH Maximum Comment Organism
7.2.2.19 6.8 7.8 pH 6.8: about 60% of maximal activity, pH 7.8: about 45% of maximal activity Sus scrofa