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Literature summary extracted from
- Studies on synthesis and degradation rates and some molecular properties of guinea-pig muscle acylphosphatase (1984), Biochem. J., 217, 499-505.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.6.1.7 | Cl- | competitive inhibition; GP1, Ki: 29.1 mM | Cavia porcellus |  |
| 3.6.1.7 | Cl- | competitive inhibition; Ho1, Ki: 40.0 mM | Equus caballus | |
| 3.6.1.7 | Cl- | competitive inhibition; T1, Ki: 40.0 mM | Meleagris gallopavo | |
| 3.6.1.7 | phosphate | competitive inhibition; GP1, Ki: 1.73 mM | Cavia porcellus | |
| 3.6.1.7 | phosphate | competitive inhibition; Ho1, Ki: 1.7 mM | Equus caballus | |
| 3.6.1.7 | phosphate | competitive inhibition; T1, Ki: 2.8 mM | Meleagris gallopavo | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.6.1.7 | additional information | - |
additional information | kinetic data | Meleagris gallopavo | |
| 3.6.1.7 | additional information | - |
additional information | kinetic data | Cavia porcellus | |
| 3.6.1.7 | additional information | - |
additional information | kinetic data | Equus caballus | |
| 3.6.1.7 | 0.57 | - |
benzoyl phosphate | GP1 | Cavia porcellus | |
| 3.6.1.7 | 1 | - |
benzoyl phosphate | T1 | Meleagris gallopavo | |
| 3.6.1.7 | 1.08 | - |
acetyl phosphate | GP1 | Cavia porcellus | |
| 3.6.1.7 | 2 | - |
benzoyl phosphate | Ho1 | Equus caballus | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.6.1.7 | cytoplasm | - |
Meleagris gallopavo | 5737 | - |
| 3.6.1.7 | cytoplasm | - |
Equus caballus | 5737 | - |
| 3.6.1.7 | cytoplasm | in proximity to sarcoplasmic reticulum | Cavia porcellus | 5737 | - |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.6.1.7 | 11370 | - |
muscle, calculated from amino acid sequence | Equus caballus |
| 3.6.1.7 | 12000 | - |
GP1, SDS-PAGE | Cavia porcellus |
| 3.6.1.7 | 12600 | - |
Ho1, SDS-PAGE | Equus caballus |
| 3.6.1.7 | 13400 | - |
T1, SDS-PAGE | Meleagris gallopavo |
| 3.6.1.7 | 24000 | - |
GP3, SDS-PAGE | Cavia porcellus |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.6.1.7 | additional information | Meleagris gallopavo | acylphosphatase seems to have a regulatory function, controlling the concentrations of highly reactive compounds such as acyl phosphates | ? | - |
? | |
| 3.6.1.7 | additional information | Cavia porcellus | acylphosphatase seems to have a regulatory function, controlling the concentrations of highly reactive compounds such as acyl phosphates | ? | - |
? | |
| 3.6.1.7 | additional information | Equus caballus | acylphosphatase seems to have a regulatory function, controlling the concentrations of highly reactive compounds such as acyl phosphates | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.6.1.7 | Cavia porcellus | - |
guinea pig | - |
| 3.6.1.7 | Cavia porcellus | - |
three molecular forms: GP1, GP2 and GP3 | - |
| 3.6.1.7 | Equus caballus | - |
- |
- |
| 3.6.1.7 | Meleagris gallopavo | - |
turkey | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.6.1.7 | - |
Cavia porcellus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.6.1.7 | muscle | skeletal muscle | Meleagris gallopavo | - |
| 3.6.1.7 | muscle | skeletal muscle | Cavia porcellus | - |
| 3.6.1.7 | muscle | skeletal muscle | Equus caballus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.6.1.7 | 3300 | - |
GP2 | Cavia porcellus |
| 3.6.1.7 | 3500 | - |
- |
Equus caballus |
| 3.6.1.7 | 3500 | - |
GP3 | Cavia porcellus |
| 3.6.1.7 | 3500 | - |
T1 | Meleagris gallopavo |
| 3.6.1.7 | 3600 | - |
GP1 | Cavia porcellus |
| 3.6.1.7 | 3800 | - |
Ho1 | Equus caballus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.6.1.7 | acetyl phosphate + H2O | - |
Cavia porcellus | acetate + phosphate | - |
? | |
| 3.6.1.7 | acetyl phosphate + H2O | - |
Equus caballus | acetate + phosphate | - |
? | |
| 3.6.1.7 | acylphosphate + H2O | specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates | Meleagris gallopavo | carboxylate + phosphate | - |
? | |
| 3.6.1.7 | acylphosphate + H2O | specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates | Cavia porcellus | carboxylate + phosphate | - |
? | |
| 3.6.1.7 | acylphosphate + H2O | specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates | Equus caballus | carboxylate + phosphate | - |
? | |
| 3.6.1.7 | benzoyl phosphate + H2O | - |
Meleagris gallopavo | benzoate + phosphate | - |
? | |
| 3.6.1.7 | benzoyl phosphate + H2O | - |
Cavia porcellus | benzoate + phosphate | - |
? | |
| 3.6.1.7 | benzoyl phosphate + H2O | - |
Equus caballus | benzoate + phosphate | - |
? | |
| 3.6.1.7 | additional information | acylphosphatase seems to have a regulatory function, controlling the concentrations of highly reactive compounds such as acyl phosphates | Meleagris gallopavo | ? | - |
? | |
| 3.6.1.7 | additional information | acylphosphatase seems to have a regulatory function, controlling the concentrations of highly reactive compounds such as acyl phosphates | Cavia porcellus | ? | - |
? | |
| 3.6.1.7 | additional information | acylphosphatase seems to have a regulatory function, controlling the concentrations of highly reactive compounds such as acyl phosphates | Equus caballus | ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.6.1.7 | GP 1-3 | multiple forms of guinea pig acylphosphatase | Cavia porcellus |
| 3.6.1.7 | GP1 | multiple forms of guinea pig acylphosphatase, major form | Cavia porcellus |
| 3.6.1.7 | GP2 | multiple forms of guinea pig acylphosphatase | Cavia porcellus |
| 3.6.1.7 | GP3 | multiple forms of guinea pig acylphosphatase | Cavia porcellus |
| 3.6.1.7 | Ho1 | multiple forms of horse acylphosphatase | Equus caballus |
| 3.6.1.7 | T1 | multiple forms of turkey acylphosphatase | Meleagris gallopavo |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.6.1.7 | 25 | - |
assay at | Meleagris gallopavo |
| 3.6.1.7 | 25 | - |
assay at | Cavia porcellus |
| 3.6.1.7 | 25 | - |
assay at | Equus caballus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.6.1.7 | 5.1 | - |
GP1 | Cavia porcellus |
| 3.6.1.7 | 5.3 | - |
assay at | Meleagris gallopavo |
| 3.6.1.7 | 5.3 | - |
assay at | Cavia porcellus |
| 3.6.1.7 | 5.3 | - |
assay at | Equus caballus |
| 3.6.1.7 | 5.3 | - |
Ho1 | Equus caballus |
| 3.6.1.7 | 5.3 | - |
T1 | Meleagris gallopavo |
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