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Literature summary extracted from

  • Friedrich, B.; Magasanik, B.
    Enzymes of agmatine degradation and the control of their synthesis in Klebsiella aerogenes (1979), J. Bacteriol., 137, 1127-1133.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.19 4-aminobutanal + NAD+ + H2O Klebsiella aerogenes degradation of agmatine 4-aminobutanoate + NADH + H+
-
 ?
1.2.1.24 succinate semialdehyde + NAD+ + H2O Klebsiella aerogenes enzyme of agmatine degradation succinate + NADH
-
 ?
1.2.1.24 succinate semialdehyde + NAD+ + H2O Klebsiella aerogenes enzyme is induced by growth on gamma-aminobutyrate succinate + NADH
-
 ?
3.5.3.11 agmatine + H2O Klebsiella aerogenes
-
 putrescine + urea
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.19 Klebsiella aerogenes
-
-
-
1.2.1.24 Klebsiella aerogenes
-
-
-
3.5.3.11 Klebsiella aerogenes
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.2.1.19 0.001
-
 NH3 used as N-source Klebsiella aerogenes
1.2.1.19 0.01
-
 histidine used as N-source Klebsiella aerogenes
1.2.1.19 0.017
-
 4-aminobutyrate used as N-source Klebsiella aerogenes
1.2.1.19 0.024
-
 putrescine used as N-source Klebsiella aerogenes

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.19 4-aminobutanal + NAD+ + H2O
-
 Klebsiella aerogenes 4-aminobutanoate + NADH + H+
-
 ?
1.2.1.19 4-aminobutanal + NAD+ + H2O degradation of agmatine Klebsiella aerogenes 4-aminobutanoate + NADH + H+
-
 ?
1.2.1.24 succinate semialdehyde + NAD+ + H2O
-
 Klebsiella aerogenes succinate + NADH
-
 ?
1.2.1.24 succinate semialdehyde + NAD+ + H2O enzyme of agmatine degradation Klebsiella aerogenes succinate + NADH
-
 ?
1.2.1.24 succinate semialdehyde + NAD+ + H2O enzyme is induced by growth on gamma-aminobutyrate Klebsiella aerogenes succinate + NADH
-
 ?
3.5.3.11 agmatine + H2O
-
 Klebsiella aerogenes putrescine + urea
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.19 NAD+
-
 Klebsiella aerogenes
1.2.1.24 NAD+
-
 Klebsiella aerogenes