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Literature summary extracted from

  • Boshoff, H.I.; Mizrahi, V.
    Purification, gene cloning, targeted knockout, overexpression, and biochemical characterization of the major pyrazinamidase from Mycobacterium smegmatis (1998), J. Bacteriol., 180, 5809-5814.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.5.1.19 expression in Escherichia coli Mycobacterium tuberculosis

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.5.1.19 0.033
-
 nicotinamide
-
 Mycobacterium tuberculosis
3.5.1.19 0.3
-
 Pyrazinamide
-
 Mycobacterium tuberculosis

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.19 Mycobacterium tuberculosis
-
-
-
3.5.1.19 Mycolicibacterium smegmatis
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.5.1.19
-
 Mycolicibacterium smegmatis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.1.19 nicotinamide + H2O
-
 Mycolicibacterium smegmatis nicotinate + NH3
-
 ?
3.5.1.19 nicotinamide + H2O
-
 Mycobacterium tuberculosis nicotinate + NH3
-
 ?
3.5.1.19 pyrazinamide + H2O
-
 Mycolicibacterium smegmatis pyrazinoic acid + NH3
-
 ?
3.5.1.19 pyrazinamide + H2O
-
 Mycobacterium tuberculosis pyrazinoic acid + NH3
-
 ?