EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.5.1.19 | Serum albumin | 0.02%, 9% activation | Mus musculus |
EC Number | General Stability | Organism |
---|---|---|
3.5.1.19 | freezing and defreezing inactivates | Mus musculus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.5.1.19 | 2-mercaptoethanol | - |
Mus musculus | |
3.5.1.19 | Ag+ | - |
Mus musculus | |
3.5.1.19 | Cu2+ | - |
Mus musculus | |
3.5.1.19 | Cys | - |
Mus musculus | |
3.5.1.19 | dithiothreitol | - |
Mus musculus | |
3.5.1.19 | EDTA | 0.02 mM, 46% inhibition | Mus musculus | |
3.5.1.19 | Fe2+ | - |
Mus musculus | |
3.5.1.19 | Hg2+ | - |
Mus musculus | |
3.5.1.19 | NAD+ | competitive with respect to nicotinamide | Mus musculus | |
3.5.1.19 | sulfhydryl reagents | - |
Mus musculus | |
3.5.1.19 | Triton X-100 | 0.1%, 24% inhibition | Mus musculus | |
3.5.1.19 | Urea | 1 M, 20% inhibition | Mus musculus | |
3.5.1.19 | Zn2+ | - |
Mus musculus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.5.1.19 | additional information | - |
additional information | - |
Mus musculus | |
3.5.1.19 | 0.006 | - |
nicotinamide | - |
Mus musculus |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.5.1.19 | Ca2+ | activation | Mus musculus | |
3.5.1.19 | Mg2+ | activation | Mus musculus | |
3.5.1.19 | Mn2+ | activation | Mus musculus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.5.1.19 | 50000 | - |
2 * 65000 + 2 * 50000, SDS-PAGE | Mus musculus |
3.5.1.19 | 65000 | - |
2 * 65000 + 2 * 50000, SDS-PAGE | Mus musculus |
3.5.1.19 | 230000 | - |
gel electrophoresis | Mus musculus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.5.1.19 | nicotinamide + H2O | Mus musculus | enzyme is induced at high nicotinamide concentrations | nicotinate + NH3 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.5.1.19 | Mus musculus | - |
- |
- |
EC Number | Posttranslational Modification | Comment | Organism |
---|---|---|---|
3.5.1.19 | glycoprotein | contains 1.7% w/w mannose and 1.5% w/w N-acetylglucosamine | Mus musculus |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.5.1.19 | - |
Mus musculus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.5.1.19 | C-1300 cell | C1300 neuroblastoma M1 clonal cell line | Mus musculus | - |
EC Number | Storage Stability | Organism |
---|---|---|
3.5.1.19 | -20°C, 50% glycerol, stable for months | Mus musculus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.5.1.19 | nicotinamide + H2O | - |
Mus musculus | nicotinate + NH3 | - |
? | |
3.5.1.19 | nicotinamide + H2O | enzyme is induced at high nicotinamide concentrations | Mus musculus | nicotinate + NH3 | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
3.5.1.19 | tetramer | 2 * 65000 + 2 * 50000, SDS-PAGE | Mus musculus |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.5.1.19 | 37 | - |
- |
Mus musculus |
EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.5.1.19 | 55 | - |
half-life: 2.5 min | Mus musculus |
3.5.1.19 | 65 | - |
half-life: 1 min | Mus musculus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.5.1.19 | 6.8 | 7.5 | - |
Mus musculus |
3.5.1.19 | 7.2 | - |
- |
Mus musculus |
3.5.1.19 | 7.5 | - |
- |
Mus musculus |