Any feedback?
Literature summary extracted from
- Selenocysteine synthase from Escherichia coli. Analysis of the reaction sequence (1991), J. Biol. Chem., 266, 6324-6328.
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 2.9.1.1 | L-Seryl-tRNASec + selenophosphate | Escherichia coli | the enzyme is involved in the biosynthesis of selenocysteine | ? | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 2.9.1.1 | Escherichia coli | - |
- |
- |
Reaction
| EC Number | Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|---|
| 2.9.1.1 | L-seryl-tRNASec + selenophosphate = L-selenocysteinyl-tRNASec + phosphate | the formyl group of pyridoxal phosphate forms a Schiff base with the alpha-amino group of L-Ser with the subsequent 2,3-elimination of a water molecule and the generation of an aminoacrylyl-tRNASecUCA intermediate | Escherichia coli |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 2.9.1.1 | L-Seryl-tRNASec + selenophosphate | - |
Escherichia coli | L-Selenocysteinyl-tRNASec + H2O + phosphate | - |
? | |
| 2.9.1.1 | L-Seryl-tRNASec + selenophosphate | the enzyme is involved in the biosynthesis of selenocysteine | Escherichia coli | ? | - |
? | |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 2.9.1.1 | pyridoxal 5'-phosphate | enzyme contains pyridoxal-phosphate | Escherichia coli | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
