EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
4.2.1.24 | 2-mercaptoethanol | required at very low concentrations of substrate | Rhodobacter capsulatus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.2.1.24 | EDTA | no inhibition | Rhodobacter capsulatus | |
4.2.1.24 | iodoacetamide | - |
Rhodobacter capsulatus | |
4.2.1.24 | additional information | insensitive to inhibition by hemin and protoporphyrin | Rhodobacter capsulatus | |
4.2.1.24 | NaCN | in presence of the substrate | Rhodobacter capsulatus | |
4.2.1.24 | NEM | - |
Rhodobacter capsulatus | |
4.2.1.24 | PCMB | - |
Rhodobacter capsulatus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.2.1.24 | 0.7 | - |
5-aminolevulinate | in presence of 2-mercaptoethanol | Rhodobacter capsulatus | |
4.2.1.24 | 2 | - |
5-aminolevulinate | in absence of 2-mercaptoethanol | Rhodobacter capsulatus |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
4.2.1.24 | additional information | does not require metallic cations for activation | Rhodobacter capsulatus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
4.2.1.24 | 260000 | - |
sucrose density gradient centrifugation | Rhodobacter capsulatus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.2.1.24 | Rhodobacter capsulatus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
4.2.1.24 | - |
Rhodobacter capsulatus |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
4.2.1.24 | 2 5-aminolevulinate = porphobilinogen + 2 H2O | substrate is covalently bound through a Schiff base | Rhodobacter capsulatus |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
4.2.1.24 | 1.62 | - |
- |
Rhodobacter capsulatus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.1.24 | 5-aminolevulinate + 5-aminolevulinate | - |
Rhodobacter capsulatus | porphobilinogen + 2 H2O | - |
? |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
4.2.1.24 | 8 | 8.6 | in citrate buffer, Tris-maleate buffer, imidazole buffer and Tris buffer | Rhodobacter capsulatus |