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Literature summary extracted from

  • Walker, R.A.
    Ncd and kinesin motor domains interact with both alpha- and beta-tubulin (1995), Proc. Natl. Acad. Sci. USA, 92, 5960-5964.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
5.6.1.3 microtubule kinesin motor domain interacts with both alpha- and beta-tubulin Drosophila sp. (in: flies) 5874
-
5.6.1.4 microtubule ncd motor domain interacts with both alpha- and beta-tubulin Drosophila sp. (in: flies) 5874
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.6.1.3 ATP + H2O + a kinesin associated with a microtubule at position n Drosophila sp. (in: flies) kinesin motor domain interacts with both alpha- and beta-tubulin ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n Drosophila melanogaster
-
ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
?
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n Drosophila sp. (in: flies) ncd motor domain interacts with both alpha- and beta-tubulin ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
?

Organism

EC Number Organism UniProt Comment Textmining
5.6.1.3 Drosophila sp. (in: flies)
-
-
-
5.6.1.4 Drosophila melanogaster
-
-
-
5.6.1.4 Drosophila sp. (in: flies)
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
5.6.1.4
-
Drosophila melanogaster

Reaction

EC Number Reaction Comment Organism Reaction ID
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end) structurally almost identical to EC3.6.4.3 (microtubule-severing ATPase) but the movement it catalyses is towards the minus end of microtubules Drosophila melanogaster

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.6.1.3 ATP + H2O + a kinesin associated with a microtubule at position n
-
Drosophila sp. (in: flies) ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
5.6.1.3 ATP + H2O + a kinesin associated with a microtubule at position n kinesin motor domain interacts with both alpha- and beta-tubulin Drosophila sp. (in: flies) ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n
-
Drosophila melanogaster ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
?
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n
-
Drosophila sp. (in: flies) ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
?
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n ncd motor domain interacts with both alpha- and beta-tubulin Drosophila sp. (in: flies) ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
?

Synonyms

EC Number Synonyms Comment Organism
5.6.1.4 ncd
-
Drosophila melanogaster
5.6.1.4 ncd
-
Drosophila sp. (in: flies)