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Literature summary extracted from

  • Walker, R.A.; Salmon, E.D.; Endow, S.A.
    The Drosophila claret segregation protein is a minus-end directed motor molecule (1990), Nature, 347, 780-782.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.6.1.4 claret segregation protein cloned and expressed in bacteria Drosophila melanogaster

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.6.1.4 5'-adenylylimidodiphosphate AMP-PNP above 2.5 mM Drosophila melanogaster
5.6.1.4 N-ethylmaleimide claret Drosophila melanogaster
5.6.1.4 V5+ claret Drosophila melanogaster

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n Drosophila melanogaster
-
 ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.6.1.4 Drosophila melanogaster
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end) structurally almost identical to EC3.6.4.3 (microtubule-severing ATPase) but the movement it catalyses is towards the minus end of microtubules Drosophila melanogaster
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n
-
 Drosophila melanogaster ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.6.1.4 claret motor protein
-
 Drosophila melanogaster