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Literature summary extracted from

  • Kuriyama, R.; Kofron, M.; Essner, R.; Kato, T.; Dragas-Granoic, S.; Omoto, C.K.; Khodjakov, A.
    Characterization of a minus end-directed kinesin-like motor protein from cultured mammalian cells (1995), J. Cell Biol., 129, 1049-1059.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.6.1.3 cDNA expression library CHO2 antigen cloned, subcloned into pVL1392 and expressed in ovarian Sf9 cells Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
5.6.1.3 66000
-
-
Homo sapiens
5.6.1.3 69000
-
calculated from amino acid sequence Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.6.1.3 ATP + H2O + a kinesin associated with a microtubule at position n Drosophila sp. (in: flies)
-
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
5.6.1.3 ATP + H2O + a kinesin associated with a microtubule at position n Homo sapiens
-
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
5.6.1.3 ATP + H2O + a kinesin associated with a microtubule at position n Arabidopsis sp.
-
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
5.6.1.3 ATP + H2O + a kinesin associated with a microtubule at position n Aspergillus sp.
-
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
5.6.1.3 ATP + H2O + a kinesin associated with a microtubule at position n Strongylocentrotus purpuratus
-
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
5.6.1.3 GTP + H2O + a kinesin associated with a microtubule at position n Drosophila sp. (in: flies)
-
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
5.6.1.3 GTP + H2O + a kinesin associated with a microtubule at position n Homo sapiens
-
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
5.6.1.3 GTP + H2O + a kinesin associated with a microtubule at position n Arabidopsis sp.
-
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
5.6.1.3 GTP + H2O + a kinesin associated with a microtubule at position n Aspergillus sp.
-
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
5.6.1.3 GTP + H2O + a kinesin associated with a microtubule at position n Strongylocentrotus purpuratus
-
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n Cricetulus griseus
-
ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
?
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n Drosophila melanogaster
-
ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
?
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n Homo sapiens
-
ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
?
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n Saccharomyces cerevisiae
-
ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
?
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n Arabidopsis sp.
-
ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
?
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n Aspergillus sp.
-
ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
?

Organism

EC Number Organism UniProt Comment Textmining
5.6.1.3 Arabidopsis sp.
-
-
-
5.6.1.3 Aspergillus sp.
-
-
-
5.6.1.3 Drosophila sp. (in: flies)
-
-
-
5.6.1.3 Homo sapiens
-
-
-
5.6.1.3 Strongylocentrotus purpuratus
-
sea urchin
-
5.6.1.4 Arabidopsis sp.
-
-
-
5.6.1.4 Aspergillus sp.
-
-
-
5.6.1.4 Cricetulus griseus
-
chinese hamster
-
5.6.1.4 Drosophila melanogaster
-
-
-
5.6.1.4 Homo sapiens
-
-
-
5.6.1.4 Saccharomyces cerevisiae
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
5.6.1.3 recombinant protein, purified from bacterial extracts Homo sapiens

Reaction

EC Number Reaction Comment Organism Reaction ID
5.6.1.3 ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. Drosophila sp. (in: flies)
5.6.1.3 ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. Homo sapiens
5.6.1.3 ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. Arabidopsis sp.
5.6.1.3 ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. Aspergillus sp.
5.6.1.3 ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. Strongylocentrotus purpuratus
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end) structurally almost identical to EC3.6.4.3 (microtubule-severing ATPase) but the movement it catalyses is towards the minus end of microtubules Cricetulus griseus
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end) structurally almost identical to EC3.6.4.3 (microtubule-severing ATPase) but the movement it catalyses is towards the minus end of microtubules Drosophila melanogaster
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end) structurally almost identical to EC3.6.4.3 (microtubule-severing ATPase) but the movement it catalyses is towards the minus end of microtubules Homo sapiens
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end) structurally almost identical to EC3.6.4.3 (microtubule-severing ATPase) but the movement it catalyses is towards the minus end of microtubules Saccharomyces cerevisiae
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end) structurally almost identical to EC3.6.4.3 (microtubule-severing ATPase) but the movement it catalyses is towards the minus end of microtubules Arabidopsis sp.
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end) structurally almost identical to EC3.6.4.3 (microtubule-severing ATPase) but the movement it catalyses is towards the minus end of microtubules Aspergillus sp.

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.6.1.3 embryo
-
Strongylocentrotus purpuratus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.6.1.3 ATP + H2O + a kinesin associated with a microtubule at position n
-
Drosophila sp. (in: flies) ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
5.6.1.3 ATP + H2O + a kinesin associated with a microtubule at position n
-
Homo sapiens ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
5.6.1.3 ATP + H2O + a kinesin associated with a microtubule at position n
-
Arabidopsis sp. ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
5.6.1.3 ATP + H2O + a kinesin associated with a microtubule at position n
-
Aspergillus sp. ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
5.6.1.3 ATP + H2O + a kinesin associated with a microtubule at position n
-
Strongylocentrotus purpuratus ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
5.6.1.3 GTP + H2O + a kinesin associated with a microtubule at position n
-
Drosophila sp. (in: flies) GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
5.6.1.3 GTP + H2O + a kinesin associated with a microtubule at position n
-
Homo sapiens GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
5.6.1.3 GTP + H2O + a kinesin associated with a microtubule at position n
-
Arabidopsis sp. GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
5.6.1.3 GTP + H2O + a kinesin associated with a microtubule at position n
-
Aspergillus sp. GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
5.6.1.3 GTP + H2O + a kinesin associated with a microtubule at position n
-
Strongylocentrotus purpuratus GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n
-
Cricetulus griseus ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
?
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n
-
Drosophila melanogaster ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
?
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n
-
Homo sapiens ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
?
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n
-
Saccharomyces cerevisiae ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
?
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n
-
Arabidopsis sp. ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
?
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n
-
Aspergillus sp. ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
?

Synonyms

EC Number Synonyms Comment Organism
5.6.1.4 Kar3
-
Saccharomyces cerevisiae
5.6.1.4 klpA
-
Aspergillus sp.
5.6.1.4 minus end-directed kinesin-like motor protein
-
Cricetulus griseus
5.6.1.4 ncd
-
Drosophila melanogaster