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Literature summary extracted from
- A role for katanin-mediated axonemal severing during Chlamydomonas deflagellation (1998), Mol. Biol., 9, 1195-1207.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 5.6.1.1 | human katanin cloned and expressed in Escherichia coli | Homo sapiens |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.6.1.1 | ADP | - |
Chlamydomonas reinhardtii |  |
| 5.6.1.1 | ADP | - |
Strongylocentrotus purpuratus | |
| 5.6.1.1 | ATPgammaS | - |
Chlamydomonas reinhardtii | |
| 5.6.1.1 | ATPgammaS | - |
Strongylocentrotus purpuratus | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 5.6.1.1 | centrosome | - |
Homo sapiens | 5813 | - |
| 5.6.1.1 | centrosome | - |
Xenopus laevis | 5813 | - |
| 5.6.1.1 | centrosome | - |
Strongylocentrotus purpuratus | 5813 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.6.1.1 | Ca2+ | - |
Chlamydomonas reinhardtii | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 5.6.1.1 | 55000 | - |
Western analysis using a polyclonal antibody against the 60 kDa subunit of human katanin | Chlamydomonas reinhardtii |
| 5.6.1.1 | 60000 | - |
- |
Homo sapiens |
| 5.6.1.1 | 60000 | - |
- |
Strongylocentrotus purpuratus |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.6.1.1 | ATP + H2O | Chlamydomonas reinhardtii | - |
ADP + phosphate | - |
? | |
| 5.6.1.1 | ATP + H2O | Homo sapiens | - |
ADP + phosphate | - |
? | |
| 5.6.1.1 | ATP + H2O | Xenopus laevis | - |
ADP + phosphate | - |
? | |
| 5.6.1.1 | ATP + H2O | Strongylocentrotus purpuratus | - |
ADP + phosphate | - |
? | |
| 5.6.1.1 | GTP + H2O | Chlamydomonas reinhardtii | - |
GDP + phosphate | - |
? | |
| 5.6.1.1 | GTP + H2O | Homo sapiens | - |
GDP + phosphate | - |
? | |
| 5.6.1.1 | GTP + H2O | Xenopus laevis | - |
GDP + phosphate | - |
? | |
| 5.6.1.1 | GTP + H2O | Strongylocentrotus purpuratus | - |
GDP + phosphate | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.6.1.1 | Chlamydomonas reinhardtii | - |
strains 137c, cc620 and cc621 | - |
| 5.6.1.1 | Homo sapiens | - |
human | - |
| 5.6.1.1 | Strongylocentrotus purpuratus | - |
sea urchin | - |
| 5.6.1.1 | Xenopus laevis | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 5.6.1.1 | - |
Chlamydomonas reinhardtii |
Reaction
| EC Number | Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|---|
| 5.6.1.1 | n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers | another member of the AAA-ATPase family, active in splitting microtubules into tubulin dimers in the centrosome | Chlamydomonas reinhardtii | |
| 5.6.1.1 | n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers | another member of the AAA-ATPase family, active in splitting microtubules into tubulin dimers in the centrosome | Homo sapiens | |
| 5.6.1.1 | n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers | another member of the AAA-ATPase family, active in splitting microtubules into tubulin dimers in the centrosome | Xenopus laevis | |
| 5.6.1.1 | n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers | another member of the AAA-ATPase family, active in splitting microtubules into tubulin dimers in the centrosome | Strongylocentrotus purpuratus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 5.6.1.1 | oocyte | - |
Xenopus laevis | - |
| 5.6.1.1 | oocyte | - |
Strongylocentrotus purpuratus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.6.1.1 | ATP + H2O | - |
Chlamydomonas reinhardtii | ADP + phosphate | - |
? | |
| 5.6.1.1 | ATP + H2O | - |
Homo sapiens | ADP + phosphate | - |
? | |
| 5.6.1.1 | ATP + H2O | - |
Xenopus laevis | ADP + phosphate | - |
? | |
| 5.6.1.1 | ATP + H2O | - |
Strongylocentrotus purpuratus | ADP + phosphate | - |
? | |
| 5.6.1.1 | GTP + H2O | - |
Chlamydomonas reinhardtii | GDP + phosphate | - |
? | |
| 5.6.1.1 | GTP + H2O | - |
Homo sapiens | GDP + phosphate | - |
? | |
| 5.6.1.1 | GTP + H2O | - |
Xenopus laevis | GDP + phosphate | - |
? | |
| 5.6.1.1 | GTP + H2O | - |
Strongylocentrotus purpuratus | GDP + phosphate | - |
? | |
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Release 2023.1 (January 2023)
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