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Literature summary extracted from

  • Mackenzie, S.M.; Brooker, M.R.; Gill, T.R.; Cox, G.B.; Howells, A.J.; Ewart, G.D.
    Mutations in the white gene of Drosophila melanogaster affecting ABC transporters that determine eye colouration (1999), Biochim. Biophys. Acta, 1419, 173-185.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
7.6.2.6 F590G major decrease in red eye color pigments, guanine transport affected Drosophila melanogaster
7.6.2.6 G243S major decrease in red and brown eye color pigments, guanine and tryptophan transport affected Drosophila melanogaster
7.6.2.6 G589E major decrease in red eye color pigments, guanine transport affected Drosophila melanogaster
7.6.2.6 H298N major decrease in red and brown eye color pigments, guanine and tryptophan transport affected Drosophila melanogaster

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.6.2.6 integral to membrane integral, protein products encoded by the white and brown genes Drosophila melanogaster
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.6.2.6 ATP + H2O + guanine/out Drosophila melanogaster
-
 ADP + phosphate + guanine/in
-
 ?
7.6.2.6 ATP + H2O + tryptophan/out Drosophila melanogaster
-
 ADP + phosphate + tryptophan/in
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
7.6.2.6 Drosophila melanogaster
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.6.2.6 ATP + H2O + guanine/out
-
 Drosophila melanogaster ADP + phosphate + guanine/in
-
 ?
7.6.2.6 ATP + H2O + tryptophan/out
-
 Drosophila melanogaster ADP + phosphate + tryptophan/in
-
 ?

Subunits

EC Number Subunits Comment Organism
7.6.2.6 More ABC-transporter Drosophila melanogaster