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Literature summary extracted from

  • Beaudoin, A.R; Sevigny, J.; Grondin, G.; Daoud, S.; Levesque, F.P.
    Purification, characterization, and localisation of two ATP diphosphohydrolase isoforms in bovine heart (1997), Am. J. Physiol., 273, 673-681.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.6.1.5 additional information no inhibition by orthovanadate; no inhibition by ouabain; no inhibition by P1,P5-di(adenosine-5'-)pentanphospate Bos taurus
3.6.1.5 NaN3
-
 Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.6.1.5 0.029
-
 ADP
-
 Bos taurus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.6.1.5 Ca2+ either Mg2+ or Ca2+ required for activity Bos taurus
3.6.1.5 Mg2+ either Mg2+ or Ca2+ required for activity Bos taurus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.6.1.5 56000
-
-
 Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.6.1.5 ADP + H2O Bos taurus
-
 AMP + phosphate
-
 ?
3.6.1.5 ATP + 2 H2O Bos taurus
-
 AMP + 2 phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.6.1.5 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.6.1.5 two ATPDase isoforms Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.6.1.5 heart ventricle, detected by immunoblotting in smooth muscle cells and endothelial cells Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.1.5 ADP + H2O
-
 Bos taurus AMP + phosphate
-
 ?
3.6.1.5 ATP + 2 H2O
-
 Bos taurus AMP + 2 phosphate
-
 ?
3.6.1.5 CDP + H2O
-
 Bos taurus CMP + phosphate
-
 ?
3.6.1.5 CTP + 2 H2O
-
 Bos taurus CMP + 2 phosphate
-
 ?
3.6.1.5 GTP + 2 H2O
-
 Bos taurus GMP + 2 phosphate
-
 ?
3.6.1.5 ITP + 2 H2O
-
 Bos taurus IMP + 2 phosphate
-
 ?
3.6.1.5 additional information no hydrolysis of GMP, UMP Bos taurus ?
-
 ?
3.6.1.5 additional information neglible hydrolysis of AMP Bos taurus ?
-
 ?
3.6.1.5 UDP + H2O
-
 Bos taurus UMP + phosphate
-
 ?
3.6.1.5 UTP + 2 H2O
-
 Bos taurus UMP + 2 phosphate
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.6.1.5 37
-
 assay at Bos taurus