Literature summary extracted from

Williams, M.V.; Parris, D.S.
Characterization of a herpes simplex virus type 2 deoxyuridine triphosphate nucleotidohydrolase and mapping of a gene conferring type specificity for the enzyme (1987), Virology, 156, 282-292.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.6.1.23	Ag+	-	Human alphaherpesvirus 2
3.6.1.23	Cu2+	-	Human alphaherpesvirus 2
3.6.1.23	EDTA	reversed by Co2+ or Mg2+	Human alphaherpesvirus 2
3.6.1.23	Hg+	-	Human alphaherpesvirus 2
3.6.1.23	Hg2+	-	Human alphaherpesvirus 2
3.6.1.23	Pb2+	-	Human alphaherpesvirus 2

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
3.6.1.23	0.0036	-	dUTP	-	Human alphaherpesvirus 2

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.6.1.23	Human alphaherpesvirus 2	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
3.6.1.23	-	Human alphaherpesvirus 2

Specific Activity [micromol/min/mg]

EC Number	Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
3.6.1.23	additional information	-	-	Human alphaherpesvirus 2

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.6.1.23	dUTP + H2O	-	Human alphaherpesvirus 2	dUMP + diphosphate	-	?

Temperature Stability [°C]

EC Number	Temperature Stability Minimum [°C]	Temperature Stability Maximum [°C]	Comment	Organism
3.6.1.23	42	-	t1/2: 18 min, in presence of 2 mM 2-mercaptoethaol	Human alphaherpesvirus 2

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Release 2023.1 (January 2023)