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Literature summary extracted from

  • Keegan, L.P.; Gerber, A.P.; Brindle, J.; Leemans, R.; Gallo, A.; Keller, W.; O'Connell, M.A.
    The properties of a tRNA-specific adenosine deaminase from Drosophila melanogaster support an evolutionary link between pre-mRNA editing and tRNA modification (2000), Mol. Cell. Biol., 20, 825-833.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.5.4.34 expressed in Pichia pastoris Drosophila melanogaster

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.5.4.34 45350
-
 x * 45350, calculated from sequence Drosophila melanogaster

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.4.34 adenine37 in tRNAAla + H2O Drosophila melanogaster
-
 hypoxanthine37 in tRNAAla + NH3
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.5.4.34 Drosophila melanogaster Q9V3R6
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.5.4.34
-
 Drosophila melanogaster

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.4.34 adenine37 in tRNAAla + H2O
-
 Drosophila melanogaster hypoxanthine37 in tRNAAla + NH3
-
 ?
3.5.4.34 adenine37 in tRNAAla + H2O the enzyme is specific for adenosine 37 of insect alanine tRNA, it has no activity on dsRNA substrates. Drosophila ADAT1 binds and deaminates tRNAAla from Bombyx mori 100fold more efficiently than the tRNAAla from Saccharomyces cerevisiae Drosophila melanogaster hypoxanthine37 in tRNAAla + NH3
-
 ?

Subunits

EC Number Subunits Comment Organism
3.5.4.34 ? x * 45350, calculated from sequence Drosophila melanogaster

Synonyms

EC Number Synonyms Comment Organism
3.5.4.34 ADAT1
-
 Drosophila melanogaster