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Literature summary extracted from
- Effect of pyrophosphate and orotidine monophosphate on cytosine deaminase regulatory properties (1988), Experientia, 41, 1563-1564.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.5.4.1 | phosphate | - |
Salmonella enterica subsp. enterica serovar Typhimurium |  |
| 3.5.4.1 | phosphate | - |
Serratia marcescens | |
| 3.5.4.1 | phosphate | - |
Pseudomonas chlororaphis subsp. aureofaciens | |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.5.4.1 | dGMP | - |
Serratia marcescens | |
| 3.5.4.1 | orotidine-5'-monophosphate | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.5.4.1 | 54000 | - |
4 * 54000, SDS-PAGE | Salmonella enterica subsp. enterica serovar Typhimurium |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.5.4.1 | cytosine + H2O | Salmonella enterica subsp. enterica serovar Typhimurium | - |
uracil + NH3 | - |
? | |
| 3.5.4.1 | cytosine + H2O | Saccharomyces cerevisiae | - |
uracil + NH3 | - |
? | |
| 3.5.4.1 | cytosine + H2O | Serratia marcescens | - |
uracil + NH3 | - |
? | |
| 3.5.4.1 | cytosine + H2O | Pseudomonas chlororaphis subsp. aureofaciens | - |
uracil + NH3 | - |
? | |
| 3.5.4.1 | cytosine + H2O | Salmonella enterica subsp. enterica serovar Typhimurium HD11-AE2 | - |
uracil + NH3 | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.5.4.1 | Pseudomonas chlororaphis subsp. aureofaciens | - |
- |
- |
| 3.5.4.1 | Saccharomyces cerevisiae | - |
- |
- |
| 3.5.4.1 | Salmonella enterica subsp. enterica serovar Typhimurium | - |
HD11-AE2 | - |
| 3.5.4.1 | Salmonella enterica subsp. enterica serovar Typhimurium HD11-AE2 | - |
HD11-AE2 | - |
| 3.5.4.1 | Serratia marcescens | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.5.4.1 | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
| 3.5.4.1 | - |
Serratia marcescens |
| 3.5.4.1 | - |
Pseudomonas chlororaphis subsp. aureofaciens |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.5.4.1 | 21.4 | - |
- |
Salmonella enterica subsp. enterica serovar Typhimurium |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.5.4.1 | 5-fluorocytosine + H2O | - |
Salmonella enterica subsp. enterica serovar Typhimurium | 5-fluorouracil + NH3 | - |
? | |
| 3.5.4.1 | 5-fluorocytosine + H2O | - |
Saccharomyces cerevisiae | 5-fluorouracil + NH3 | - |
? | |
| 3.5.4.1 | 5-fluorocytosine + H2O | - |
Salmonella enterica subsp. enterica serovar Typhimurium HD11-AE2 | 5-fluorouracil + NH3 | - |
? | |
| 3.5.4.1 | cytosine + H2O | - |
Salmonella enterica subsp. enterica serovar Typhimurium | uracil + NH3 | - |
? | |
| 3.5.4.1 | cytosine + H2O | - |
Saccharomyces cerevisiae | uracil + NH3 | - |
? | |
| 3.5.4.1 | cytosine + H2O | - |
Serratia marcescens | uracil + NH3 | - |
? | |
| 3.5.4.1 | cytosine + H2O | - |
Pseudomonas chlororaphis subsp. aureofaciens | uracil + NH3 | - |
? | |
| 3.5.4.1 | cytosine + H2O | - |
Salmonella enterica subsp. enterica serovar Typhimurium HD11-AE2 | uracil + NH3 | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.5.4.1 | tetramer | 4 * 54000, SDS-PAGE | Salmonella enterica subsp. enterica serovar Typhimurium |
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