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Literature summary extracted from

  • Campo, M.L.; Fuentes, J.M.; Soler, G.
    An arginine regulated gamma-guanidobutyrate ureahydrolase from tench liver (Tinca tinca L.) (1992), Arch. Int. Physiol. Biochim. Biophys., 100, 55-60.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.3.7 Mn2+ 5 mM complete inhibition Tinca tinca
3.5.3.7 Zn2+ 92% inhibition Tinca tinca

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.5.3.7 45
-
 4-guanidinobutyric acid 5 mM arginine added Tinca tinca
3.5.3.7 100 200 L-arginine
-
 Tinca tinca
3.5.3.7 230
-
 4-guanidinobutyric acid
-
 Tinca tinca
3.5.3.7 450
-
 4-guanidopropionic acid
-
 Tinca tinca
3.5.3.7 1670
-
 L-(+)-(S)-canavanine
-
 Tinca tinca

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.5.3.7 Mn2+
-
 Pseudomonas fluorescens
3.5.3.7 Mn2+
-
 Pseudomonas putida
3.5.3.7 Mn2+
-
 Streptomyces griseus
3.5.3.7 Mn2+
-
 Helix pomatia
3.5.3.7 Mn2+
-
 Penicillium roqueforti
3.5.3.7 Mn2+
-
 Gallus sp.
3.5.3.7 Mn2+
-
 Iguania
3.5.3.7 Mn2+
-
 Raja clavata
3.5.3.7 Mn2+ absolute requirement for its arginase activity Tinca tinca

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.5.3.7 35000
-
 6 * 35000 Tinca tinca
3.5.3.7 170000
-
-
 Tinca tinca

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.3.7 4-Guanidinobutyrate + H2O Pseudomonas fluorescens
-
 4-Aminobutyrate + urea
-
 ?
3.5.3.7 4-Guanidinobutyrate + H2O Pseudomonas putida
-
 4-Aminobutyrate + urea
-
 ?
3.5.3.7 4-Guanidinobutyrate + H2O Streptomyces griseus
-
 4-Aminobutyrate + urea
-
 ?
3.5.3.7 4-Guanidinobutyrate + H2O Helix pomatia
-
 4-Aminobutyrate + urea
-
 ?
3.5.3.7 4-Guanidinobutyrate + H2O Penicillium roqueforti
-
 4-Aminobutyrate + urea
-
 ?
3.5.3.7 4-Guanidinobutyrate + H2O Gallus sp.
-
 4-Aminobutyrate + urea
-
 ?
3.5.3.7 4-Guanidinobutyrate + H2O Iguania
-
 4-Aminobutyrate + urea
-
 ?
3.5.3.7 4-Guanidinobutyrate + H2O Raja clavata
-
 4-Aminobutyrate + urea
-
 ?
3.5.3.7 4-Guanidinobutyrate + H2O Tinca tinca
-
 4-Aminobutyrate + urea
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.5.3.7 Gallus sp.
-
 chicken
-
3.5.3.7 Helix pomatia
-
 snail
-
3.5.3.7 Iguania
-
-
-
3.5.3.7 Penicillium roqueforti
-
-
-
3.5.3.7 Pseudomonas fluorescens
-
-
-
3.5.3.7 Pseudomonas putida
-
 P2 (ATCC 25571)
-
3.5.3.7 Raja clavata
-
 ray
-
3.5.3.7 Streptomyces griseus
-
-
-
3.5.3.7 Tinca tinca
-
 teleostan fresh-water tench, autochtonous fish, L.
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.5.3.7
-
 Tinca tinca

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.3.7 hepatopancreas
-
 Helix pomatia
-
3.5.3.7 liver
-
 Gallus sp.
-
3.5.3.7 liver
-
 Iguania
-
3.5.3.7 liver
-
 Raja clavata
-
3.5.3.7 liver
-
 Tinca tinca
-

Storage Stability

EC Number Storage Stability Organism
3.5.3.7 4°C, quite stable, retains basically the same activity several weeks, temperatures below 0°C have negative effects Tinca tinca

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.3.7 3-guanidopropionate + H2O
-
 Tinca tinca ?
-
 ?
3.5.3.7 4-Guanidinobutyrate + H2O
-
 Pseudomonas fluorescens 4-Aminobutyrate + urea
-
 ?
3.5.3.7 4-Guanidinobutyrate + H2O
-
 Pseudomonas putida 4-Aminobutyrate + urea
-
 ?
3.5.3.7 4-Guanidinobutyrate + H2O
-
 Streptomyces griseus 4-Aminobutyrate + urea
-
 ?
3.5.3.7 4-Guanidinobutyrate + H2O
-
 Helix pomatia 4-Aminobutyrate + urea
-
 ?
3.5.3.7 4-Guanidinobutyrate + H2O
-
 Penicillium roqueforti 4-Aminobutyrate + urea
-
 ?
3.5.3.7 4-Guanidinobutyrate + H2O
-
 Gallus sp. 4-Aminobutyrate + urea
-
 ?
3.5.3.7 4-Guanidinobutyrate + H2O
-
 Iguania 4-Aminobutyrate + urea
-
 ?
3.5.3.7 4-Guanidinobutyrate + H2O
-
 Raja clavata 4-Aminobutyrate + urea
-
 ?
3.5.3.7 4-Guanidinobutyrate + H2O
-
 Tinca tinca 4-Aminobutyrate + urea
-
 ?
3.5.3.7 4-guanidopropionic acid + H2O
-
 Tinca tinca 3-aminopropionate + urea
-
 ?
3.5.3.7 arginine + H2O
-
 Tinca tinca 2,5-diaminopentanoate + urea
-
 ?
3.5.3.7 L-canavanine + H2O
-
 Tinca tinca L-2-amino-4-(aminooxy)butanoic acid + urea
-
 ?

Subunits

EC Number Subunits Comment Organism
3.5.3.7 hexamer 6 * 35000 Tinca tinca

Synonyms

EC Number Synonyms Comment Organism
3.5.3.7 tench liver isoenzyme II
-
 Tinca tinca

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.5.3.7 45
-
 no variation up to, higher temperatures have negative effect Tinca tinca

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.5.3.7 9.5
-
-
 Pseudomonas fluorescens
3.5.3.7 9.5
-
-
 Pseudomonas putida
3.5.3.7 9.5
-
-
 Streptomyces griseus
3.5.3.7 9.5
-
-
 Helix pomatia
3.5.3.7 9.5
-
-
 Penicillium roqueforti
3.5.3.7 9.5
-
-
 Gallus sp.
3.5.3.7 9.5
-
-
 Iguania
3.5.3.7 9.5
-
-
 Raja clavata

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.5.3.7 4 11
-
 Tinca tinca