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Literature summary extracted from

  • Takahashi, S.; Ohashi, T.; Kii, Y.; Kumagai, H.; Yamada, H.
    Microbial transformation of hydantoins to N-carbamyl-D-amino acids (1979), J. Ferment. Technol., 57, 328-332.
No PubMed abstract available

Application

EC Number Application Comment Organism
3.5.2.2 medicine D-amino acids for preparation of beta-lactam antibiotics like semisynthetic penicillins and cephalosporins such as ampicillin, amoxicillin and cefadroxyl, peptide hormones and pesticides Pseudomonas putida

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.2.2 5,6-dihydrouracil + H2O Enterobacter cloacae
-
3-ureidopropionate
-
?
3.5.2.2 5,6-dihydrouracil + H2O Pseudomonas putida
-
3-ureidopropionate
-
?
3.5.2.2 5,6-dihydrouracil + H2O Streptomyces griseus
-
3-ureidopropionate
-
?
3.5.2.2 5,6-dihydrouracil + H2O Clavibacter michiganensis subsp. sepedonicus
-
3-ureidopropionate
-
?
3.5.2.2 hydantoin + H2O Enterobacter cloacae
-
N-carbamoyl glycine
-
?
3.5.2.2 hydantoin + H2O Pseudomonas putida
-
N-carbamoyl glycine
-
?
3.5.2.2 hydantoin + H2O Streptomyces griseus
-
N-carbamoyl glycine
-
?
3.5.2.2 hydantoin + H2O Clavibacter michiganensis subsp. sepedonicus
-
N-carbamoyl glycine
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.5.2.2 Clavibacter michiganensis subsp. sepedonicus
-
-
-
3.5.2.2 Enterobacter cloacae
-
-
-
3.5.2.2 Pseudomonas putida
-
-
-
3.5.2.2 Streptomyces griseus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.2.2 5,6-dihydrouracil + H2O
-
Enterobacter cloacae 3-ureidopropionate
-
?
3.5.2.2 5,6-dihydrouracil + H2O
-
Pseudomonas putida 3-ureidopropionate
-
?
3.5.2.2 5,6-dihydrouracil + H2O
-
Streptomyces griseus 3-ureidopropionate
-
?
3.5.2.2 5,6-dihydrouracil + H2O
-
Clavibacter michiganensis subsp. sepedonicus 3-ureidopropionate
-
?
3.5.2.2 DL-5-(p-hydroxyphenyl)hydantoin + H2O
-
Enterobacter cloacae N-carbamoyl-p-hydroxyphenylglycine
-
?
3.5.2.2 DL-5-(p-hydroxyphenyl)hydantoin + H2O
-
Pseudomonas putida N-carbamoyl-p-hydroxyphenylglycine
-
?
3.5.2.2 DL-5-(p-hydroxyphenyl)hydantoin + H2O
-
Clavibacter michiganensis subsp. sepedonicus N-carbamoyl-p-hydroxyphenylglycine
-
?
3.5.2.2 hydantoin + H2O
-
Enterobacter cloacae N-carbamoyl glycine
-
?
3.5.2.2 hydantoin + H2O
-
Pseudomonas putida N-carbamoyl glycine
-
?
3.5.2.2 hydantoin + H2O
-
Streptomyces griseus N-carbamoyl glycine
-
?
3.5.2.2 hydantoin + H2O
-
Clavibacter michiganensis subsp. sepedonicus N-carbamoyl glycine
-
?
3.5.2.2 m-chlorophenylhydantoin + H2O
-
Enterobacter cloacae ?
-
?
3.5.2.2 m-chlorophenylhydantoin + H2O
-
Pseudomonas putida ?
-
?
3.5.2.2 m-chlorophenylhydantoin + H2O
-
Clavibacter michiganensis subsp. sepedonicus ?
-
?
3.5.2.2 p-chlorophenylhydantoin + H2O
-
Enterobacter cloacae ?
-
?
3.5.2.2 p-chlorophenylhydantoin + H2O
-
Pseudomonas putida ?
-
?
3.5.2.2 p-chlorophenylhydantoin + H2O
-
Clavibacter michiganensis subsp. sepedonicus ?
-
?