Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Kaziro, Y.; Ochoa, S.; Warner, R.C.; Chen, J.Y.
    Metabolism of propionic acid in animal tissues. VIII. Crystalline propionyl carboxylase (1961), J. Biol. Chem., 236, 1917-1923.
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
6.4.1.3
-
Sus scrofa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.4.1.3 0.2
-
propanoyl-CoA
-
Sus scrofa
6.4.1.3 1.5
-
butanoyl-CoA
-
Sus scrofa

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
6.4.1.3 690000
-
calculation from sedimentation and diffusion data Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
6.4.1.3 Sus scrofa
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
6.4.1.3 5.6
-
-
Sus scrofa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.4.1.3 ATP + acetyl-CoA + HCO3- at 0.7% of the velocity compared to propanoyl-CoA Sus scrofa ADP + phosphate + malonyl-CoA
-
?
6.4.1.3 ATP + butanoyl-CoA + HCO3- at 5.7% of the velocity compared to propanoyl-CoA Sus scrofa ADP + phosphate + ?
-
?
6.4.1.3 ATP + crotonyl-CoA + HCO3- at 3% the velocity compared to propanoyl-CoA Sus scrofa ADP + phosphate + ?
-
?
6.4.1.3 ATP + propanoyl-CoA + HCO3-
-
Sus scrofa ADP + phosphate + methylmalonyl-CoA
-
?

Cofactor

EC Number Cofactor Comment Organism Structure
6.4.1.3 biotin 4 mol of biotin bound per mol of enzyme Sus scrofa