Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Attwood, P.V.
    The structure and the mechanism of action of pyruvate carboxylase (1995), Int. J. Biochem. Cell Biol., 27, 231-249.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
6.4.1.1 acetyl-CoA
-
 Gallus gallus
6.4.1.1 acetyl-CoA
-
 Aspergillus nidulans
6.4.1.1 acetyl-CoA highly dependent on vertebrata
6.4.1.1 acetyl-CoA quite active in absence of acetyl-CoA Saccharomyces cerevisiae

General Stability

EC Number General Stability Organism
6.4.1.1 acetyl-CoA stabilizes quarternary structure of the enzyme Gallus gallus
6.4.1.1 acetyl-CoA stabilizes quarternary structure of the enzyme Aspergillus nidulans

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
6.4.1.1 Mn2+
-
 Gallus gallus
6.4.1.1 Mn2+ each subunit contains one tightly bound metal ion, predominantly Mn2+, or mixtures of Mn2+ and Mg2+ vertebrata
6.4.1.1 Zinc each subunit contains one tightly bound Zn2+ Saccharomyces cerevisiae

Organism

EC Number Organism UniProt Comment Textmining
6.4.1.1 Aspergillus nidulans
-
-
-
6.4.1.1 Gallus gallus
-
-
-
6.4.1.1 Pseudomonas citronellolis
-
-
-
6.4.1.1 Saccharomyces cerevisiae
-
-
-
6.4.1.1 vertebrata
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
6.4.1.1 ATP + pyruvate + HCO3- + H+ = ADP + phosphate + oxaloacetate mechanism, overview vertebrata
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.4.1.1 liver
-
 Gallus gallus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.4.1.1 ATP + pyruvate + HCO3-
-
 Gallus gallus ADP + phosphate + oxaloacetate
-
 ?
6.4.1.1 ATP + pyruvate + HCO3-
-
 Saccharomyces cerevisiae ADP + phosphate + oxaloacetate
-
 ?
6.4.1.1 ATP + pyruvate + HCO3-
-
 Aspergillus nidulans ADP + phosphate + oxaloacetate
-
 ?
6.4.1.1 ATP + pyruvate + HCO3-
-
 Pseudomonas citronellolis ADP + phosphate + oxaloacetate
-
 ?
6.4.1.1 ATP + pyruvate + HCO3-
-
 vertebrata ADP + phosphate + oxaloacetate
-
 ?