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Literature summary extracted from

  • Weissmann, B.; Chao, H.; Chow, P.
    A glucosamine O,N-disulfate O-sulfohydrolase with a probable role in mammalian catabolism of heparan sulfate (1980), Biochem. Biophys. Res. Commun., 97, 827-833.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.6.11 NaCl 0.16 M 50% inhibition Bos taurus
3.1.6.11 PO43- 0.2 mM 22% inhibition Bos taurus
3.1.6.11 SO32- 0.2 mM 97% inhibition Bos taurus
3.1.6.11 SO42- 0.2 mM 43% inhibition Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.6.11 heparan sulfate + H2O Bos taurus
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.6.11 Bos taurus
-
 cow
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.6.11 partial Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.6.11 kidney
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.6.11 (glucosamine O,N-disulfate)-(iduronic acid O-sulfate)-(3H-anhydromannitol O-sulfate) + H2O substrate prepared from degradation products of heparin Bos taurus ?
-
 ?
3.1.6.11 heparan sulfate + H2O
-
 Bos taurus ?
-
 ?
3.1.6.11 methyl glycoside 6-O-sulfate + H2O
-
 Bos taurus ?
-
 ?
3.1.6.11 methyl-2-sulfamino2-deoxy-alpha-D-glucopyranoside 3-sulfate + H2O
-
 Bos taurus ?
-
 ?
3.1.6.11 methyl-2-sulfamino2-deoxy-alpha-D-glucopyranoside 6-sulfate + H2O
-
 Bos taurus ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.6.11 4.1
-
-
 Bos taurus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.1.6.11 0.16
-
 NaCl
-
 Bos taurus