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Literature summary extracted from

  • Lenz, R.; Zenk, M.H.
    Acetyl coenzyme A:salutaridinol-7-O-acetyltransferase from Papaver somniferum plant cell cultures (1995), J. Biol. Chem., 270, 31091-31096.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.150 1,10-phenanthroline 0.1 mM, 56% inhibition Papaver somniferum
2.3.1.150 8-hydroxyquinoline 0.1 mM, 85% inhibition Papaver somniferum
2.3.1.150 Cd2+ 1 mM, strong Papaver somniferum
2.3.1.150 codeinone 0.5 mM, 55% inhibition Papaver somniferum
2.3.1.150 Cu2+ 1 mM, strong Papaver somniferum
2.3.1.150 Diethyldithiocarbamic acid sodium salt 0.05 mM, 87% inhibition Papaver somniferum
2.3.1.150 NEM weak Papaver somniferum
2.3.1.150 p-chloromercuribenzoate weak Papaver somniferum
2.3.1.150 salutaridine 0.5 mM, 74% inhibition Papaver somniferum
2.3.1.150 thebaine 0.5 mM, 76% inhibition Papaver somniferum
2.3.1.150 Zn2+ 1 mM, strong Papaver somniferum

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.150 0.007
-
 salutaridinol
-
 Papaver somniferum
2.3.1.150 0.046
-
 acetyl-CoA
-
 Papaver somniferum
2.3.1.150 0.068
-
 n-propionyl-CoA
-
 Papaver somniferum
2.3.1.150 0.093
-
 n-hexanoyl-CoA
-
 Papaver somniferum

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.150 50000
-
 1 * 50000, SDS-PAGE Papaver somniferum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.150 Acetyl-CoA + salutaridinol Papaver somniferum the enzyme catalyzes the formation of thebaine in morphine biosynthesis ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.150 no activity in Papaver rhoeas
-
 cell cultures
-
2.3.1.150 Papaver bracteatum
-
-
-
2.3.1.150 Papaver somniferum
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.150
-
 Papaver somniferum

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.150 cell culture
-
 Papaver somniferum
-
2.3.1.150 cell suspension culture
-
 Papaver bracteatum
-
2.3.1.150 leaf
-
 Papaver somniferum
-
2.3.1.150 plant capsule
-
 Papaver somniferum
-
2.3.1.150 root
-
 Papaver somniferum
-
2.3.1.150 shoot
-
 Papaver somniferum
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.150 additional information
-
-
 Papaver somniferum

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.150 Acetyl-CoA + nudaurine
-
 Papaver somniferum ?
-
 ?
2.3.1.150 acetyl-CoA + salutaridinol
-
 Papaver somniferum CoA + 7-O-acetylsalutaridinol
-
 ?
2.3.1.150 acetyl-CoA + salutaridinol
-
 Papaver bracteatum CoA + 7-O-acetylsalutaridinol
-
 ?
2.3.1.150 Acetyl-CoA + salutaridinol the enzyme catalyzes the formation of thebaine in morphine biosynthesis Papaver somniferum ?
-
 ?
2.3.1.150 n-Hexanoyl-CoA + salutaridinol
-
 Papaver somniferum ?
-
 ?
2.3.1.150 n-Propionyl-CoA + salutaridinol
-
 Papaver somniferum ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.1.150 ? 1 * 50000, SDS-PAGE Papaver somniferum

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.150 47
-
-
 Papaver somniferum

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.150 6 9
-
 Papaver somniferum