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Literature summary extracted from

  • Fleshood, H.L.; Pitot, H.C.
    The metabolism of O-phosphorylethanolamine in animal tissues. I. O-phosphorylethanolamine phospho-lyase: partial purification and characterization (1970), J. Biol. Chem., 245, 4414-4420.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.2.3.2 Ag+ 0.1 mM, 92% inhibition Oryctolagus cuniculus
4.2.3.2 Ag+ 0.1 mM, 92% inhibition Rattus norvegicus
4.2.3.2 Cd2+ 0.1 mM, 100% inhibition Oryctolagus cuniculus
4.2.3.2 Cd2+ 0.1 mM, 100% inhibition Rattus norvegicus
4.2.3.2 CN- 1 mM, 88% inhibition Oryctolagus cuniculus
4.2.3.2 CN- 1 mM, 88% inhibition Rattus norvegicus
4.2.3.2 Co2+ 0.1 mM, 25% inhibition Oryctolagus cuniculus
4.2.3.2 Co2+ 0.1 mM, 25% inhibition Rattus norvegicus
4.2.3.2 Cu2+ 0.1 mM, 94% inhibition Oryctolagus cuniculus
4.2.3.2 Cu2+ 0.1 mM, 94% inhibition Rattus norvegicus
4.2.3.2 NaBH4
-
 Oryctolagus cuniculus
4.2.3.2 p-chloromercuribenzoate 0.1 mM, 98.4% inhibition Oryctolagus cuniculus
4.2.3.2 p-chloromercuribenzoate 0.1 mM, 98.4% inhibition Rattus norvegicus
4.2.3.2 Pb2+ 0.1 mM, 75% inhibition Oryctolagus cuniculus
4.2.3.2 Pb2+ 0.1 mM, 75% inhibition Rattus norvegicus
4.2.3.2 SO42- 10 mM, 49% inhibition Oryctolagus cuniculus
4.2.3.2 SO42- 10 mM, 49% inhibition Rattus norvegicus
4.2.3.2 Zn2+ 0.1 mM, 91% inhibition Oryctolagus cuniculus
4.2.3.2 Zn2+ 0.1 mM, 91% inhibition Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.2.3.2 0.61
-
 Ethanolamine phosphate
-
 Rattus norvegicus
4.2.3.2 0.63
-
 Ethanolamine phosphate
-
 Oryctolagus cuniculus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.2.3.2 168000
-
 gel filtration Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
4.2.3.2 Oryctolagus cuniculus
-
-
-
4.2.3.2 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.2.3.2
-
 Rattus norvegicus
4.2.3.2
-
 Oryctolagus cuniculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.2.3.2 liver
-
 Rattus norvegicus
-
4.2.3.2 liver
-
 Oryctolagus cuniculus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.2.3.2 0.073
-
-
 Rattus norvegicus
4.2.3.2 0.914
-
-
 Oryctolagus cuniculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.3.2 ethanolamine phosphate + H2O
-
 Rattus norvegicus acetaldehyde + NH3 + phosphate
-
 ?
4.2.3.2 ethanolamine phosphate + H2O
-
 Oryctolagus cuniculus acetaldehyde + NH3 + phosphate
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.2.3.2 7.5 8
-
 Rattus norvegicus
4.2.3.2 7.5 8
-
 Oryctolagus cuniculus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
4.2.3.2 6.7 8.6 less than 50% of maximal activity above and below Rattus norvegicus
4.2.3.2 6.7 8.6 less than 50% of maximal activity above and below Oryctolagus cuniculus

Cofactor

EC Number Cofactor Comment Organism Structure
4.2.3.2 pyridoxal 5'-phosphate required, Km: 0.00027 mM Rattus norvegicus
4.2.3.2 pyridoxal 5'-phosphate required, Km: 0.00027 mM Oryctolagus cuniculus