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Literature summary extracted from

  • Kusiak, J.W.; Quirk, J.M.; Brady, R.O.
    Ceramide trihexosidase from human placenta (1978), Methods Enzymol., 50, 533-537.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.2.1.22 additional information
-
 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.2.1.22 1.55
-
 4-methylumbelliferyl-alpha-D-galactopyranoside
-
 Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.2.1.22 103000
-
 gel filtration Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.2.1.22 D-galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine + H2O Homo sapiens
-
 lactosyl-N-acylsphingosine + D-galactose
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.22 Homo sapiens
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.2.1.22 glycoprotein contains sialic acid, multiple forms differ in sialic acid content Homo sapiens

Purification (Commentary)

EC Number Purification (Comment) Organism
3.2.1.22
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.22 placenta
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.2.1.22 4.02
-
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.22 4-methylumbelliferyl-alpha-D-galactopyranoside + H2O
-
 Homo sapiens ?
-
 ?
3.2.1.22 ceramide trihexoside + H2O
-
 Homo sapiens ?
-
 ?
3.2.1.22 D-galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine + H2O
-
 Homo sapiens lactosyl-N-acylsphingosine + D-galactose
-
 ?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.2.1.22 52
-
 1 h, 90% loss of activity Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.2.1.22 4.1
-
 D-galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine Homo sapiens
3.2.1.22 4.4
-
 4-methylumbelliferyl-alpha-D-galactopyranoside Homo sapiens