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Literature summary extracted from

  • Vagelos, P.R.; Larrabee, A.R.
    Acyl carrier protein. IX. Acyl carrier protein hydrolase (1967), J. Biol. Chem., 242, 1776-1781.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.4.14 2-mercaptoethanol required Escherichia coli
3.1.4.14 dithiothreitol required Escherichia coli

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.4.14 0.0017
-
acyl-carrier protein
-
Escherichia coli

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.4.14 Co2+ required, or other divalent cations Escherichia coli
3.1.4.14 Fe2+ required, or other divalent cations Escherichia coli
3.1.4.14 Mg2+ required, or other divalent cations Escherichia coli
3.1.4.14 Mn2+ required, or other divalent cations Escherichia coli
3.1.4.14 Zn2+ required, or other divalent cations Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.4.14 acyl-carrier protein + H2O Escherichia coli CoA donates 4'-phosphopantetheine as prosthetic group 4'-phosphopantetheine + apoprotein
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.14 Escherichia coli
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.4.14 partial Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.14 acyl-carrier protein + H2O CoA donates 4'-phosphopantetheine as prosthetic group Escherichia coli 4'-phosphopantetheine + apoprotein
-
?
3.1.4.14 Clostridium butyricum acyl-carrier protein + H2O
-
Escherichia coli 4'-phosphopantetheine + apoprotein acyl-carrier protein
-
?
3.1.4.14 E. coli acyl-carrier protein + H2O no activity on large peptides of E. coli acyl-carrier-protein Escherichia coli 4'-phosphopantetheine + apoprotein of acyl-carrier protein
-
?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.4.14 8.5 10.5
-
Escherichia coli

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.1.4.14 7.2
-
not active below Escherichia coli