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Literature summary extracted from

  • Gieselmann, V.; Hasilik, A.; von Figura, K.
    Tartrate-inhibitable acid phosphatase. Purification from placenta, characterization and subcellular distribution in fibroblasts (1984), Hoppe-Seyler's Z. Physiol. Chem., 365, 651-660.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.2 phosphate
-
 Homo sapiens
3.1.3.2 Tartrate
-
 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.3.2 0.2
-
 p-nitrophenyl phosphate
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.3.2 lysosome
-
 Homo sapiens 5764
-
3.1.3.2 additional information light membrane-fraction Homo sapiens
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.3.2 48000
-
 2 * 48000, urinary enzyme, SDS-PAGE Homo sapiens
3.1.3.2 90000
-
 gel filtration Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.2 Homo sapiens
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.1.3.2 glycoprotein each subunit carries one oligosaccharide of the high-mannose/hybride type Homo sapiens

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.3.2 isoenzyme A, B and C 103 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.2 fibroblast normal and mucolipidosis II fibroblasts Homo sapiens
-
3.1.3.2 placenta
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.3.2 236
-
-
 Homo sapiens

Storage Stability

EC Number Storage Stability Organism
3.1.3.2 -20°C, 50% glycerol, 15 months, stable Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.2 AMP + H2O
-
 Homo sapiens adenosine + phosphate
-
 ?
3.1.3.2 ATP + H2O no activity Homo sapiens ADP + phosphate
-
 ?
3.1.3.2 diphosphate + H2O no activity Homo sapiens 2 phosphate
-
 ?
3.1.3.2 Glucose 6-phosphate + H2O
-
 Homo sapiens Glucose + phosphate
-
 ?
3.1.3.2 NADP+ + H2O no activity Homo sapiens NAD+ + phosphate
-
 ?
3.1.3.2 p-nitrophenyl phosphate + H2O
-
 Homo sapiens p-nitrophenol + phosphate
-
 ?
3.1.3.2 UTP + 2 H2O no activity Homo sapiens UMP + 2 phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.3.2 dimer 2 * 48000, urinary enzyme, SDS-PAGE Homo sapiens

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.1.3.2 20
-
 20 h, stable Homo sapiens
3.1.3.2 37
-
 20 h, 27% loss of activity Homo sapiens
3.1.3.2 50
-
 90 min, 74% loss of activity Homo sapiens
3.1.3.2 70
-
 10 min, more than 95% loss of activity Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.3.2 4
-
-
 Homo sapiens