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Literature summary extracted from
- Peptides isolated from Enterobacter nuclease as potential polyamine binding sites (1976), Biochim. Biophys. Acta, 432, 369-380.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.6.1.21 | putrescine | enhances activity against poly(C) and yeast RNA | Enterobacter sp. |  |
| 4.6.1.21 | spermidine | enhances activity against poly(C) and yeast RNA, reverses inhibition by poly(G) by removal of inhibitor from the enzymes surface | Enterobacter sp. | |
| 4.6.1.21 | spermine | enhances activity against poly(C) and yeast RNA, reverses inhibition by poly(G) by removal of inhibitor from the enzymes surface | Enterobacter sp. | |
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 4.6.1.21 | analysis | - |
Enterobacter sp. |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.6.1.21 | Poly(A) | - |
Enterobacter sp. | |
| 4.6.1.21 | Poly(G) | inhibition at a concentration of 0.25 nM is complete | Enterobacter sp. | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.6.1.21 | Ca2+ | stimulating | Enterobacter sp. | |
| 4.6.1.21 | Mg2+ | stimulating | Enterobacter sp. | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.6.1.21 | RNA + H2O | Enterobacter sp. | preferential cleavage at CpA | nucleoside 3'-phosphates and 3'-phosphooligonucleotides and 2',3'-cyclic phosphates | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.6.1.21 | Enterobacter sp. | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 4.6.1.21 | - |
Enterobacter sp. |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 4.6.1.21 | -20°C | Enterobacter sp. |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.6.1.21 | RNA + H2O | preferential cleavage at CpA | Enterobacter sp. | nucleoside 3'-phosphates and 3'-phosphooligonucleotides and 2',3'-cyclic phosphates | - |
? | |
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