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Literature summary extracted from

  • De-Eknamkul, W.; Zenk, M.H.
    Enzymic formation of (R)-reticuline from 1,2-dehydroreticuline in the opium poppy plant (1990), Tetrahedron Lett., 31, 4855-4858.
No PubMed abstract available

General Stability

EC Number General Stability Organism
1.5.1.27 stablilized by NADPH, 1 mM Papaver somniferum

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.5.1.27 0.007
-
 NADPH
-
 Papaver somniferum
1.5.1.27 0.01
-
 1,2-dehydroreticuline
-
 Papaver somniferum

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.5.1.27 cytosol
-
 Papaver somniferum 5829
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.5.1.27 30000
-
 gel filtration Papaver somniferum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.5.1.27 1,2-Dehydroreticuline + NADPH Papaver somniferum formation of the precursor of morphinan alkaloids ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.5.1.27 no activity in Argemone hunnemannii
-
-
-
1.5.1.27 no activity in Dicentra spectabilis
-
-
-
1.5.1.27 no activity in Fumaria macrosepta
-
-
-
1.5.1.27 no activity in Papaver oreophilum
-
-
-
1.5.1.27 no activity in Papaver persicum
-
-
-
1.5.1.27 Papaver bracteatum
-
-
-
1.5.1.27 Papaver somniferum
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.5.1.27 additional information no activity in cell cultures Papaver somniferum
-
1.5.1.27 additional information no activity in cell cultures Papaver bracteatum
-
1.5.1.27 seedling
-
 Papaver somniferum
-

Storage Stability

EC Number Storage Stability Organism
1.5.1.27 -20°C, 1 mM NADPH, 50% loss of activity after 30 days Papaver bracteatum
1.5.1.27 4°C, 1 mM NADPH, 50% loss of activity after 20 days Papaver somniferum

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.1.27 1,2-Dehydroreticuline + NADPH formation of the precursor of morphinan alkaloids Papaver somniferum ?
-
 ?
1.5.1.27 1,2-dehydroreticuline + NADPH + H+
-
 Papaver somniferum (R)-reticuline + NADP+
-
 ?
1.5.1.27 1,2-dehydroreticuline + NADPH + H+
-
 Papaver bracteatum (R)-reticuline + NADP+
-
 ?

Subunits

EC Number Subunits Comment Organism
1.5.1.27 monomer 1 * 30000, SDS-PAGE Papaver somniferum

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.5.1.27 30
-
-
 Papaver somniferum

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.5.1.27 8.5
-
-
 Papaver somniferum