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Literature summary extracted from
- Deoxyribonuclease II purified from the isolated lysosomes of porcine spleen and from porcine liver homogenates. Comparison with deoxyribonuclease II purified from porcine spleen homogenates (1989), Biochim. Biophys. Acta, 1007, 15-22.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.22.1 | iodoacetate | complete inhibition at 0.2 mM | Sus scrofa |  |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.1.22.1 | lysosome | enriched in porcine spleen | Sus scrofa | 5764 | - |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.1.22.1 | 10000 | - |
alphabeta, 1 * 35000 + 1 * 10000, SDS-PAGE, gel filtration | Sus scrofa |
| 3.1.22.1 | 35000 | - |
alphabeta, 1 * 35000 + 1 * 10000, SDS-PAGE, gel filtration | Sus scrofa |
| 3.1.22.1 | 45000 | 46000 | gel filtration, SDS-PAGE | Sus scrofa |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.22.1 | DNA + H2O | Sus scrofa | - |
oligonucleotides + ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.22.1 | Sus scrofa | - |
- |
- |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 3.1.22.1 | glycoprotein | - |
Sus scrofa |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.1.22.1 | to homogeneity by 4-6step chromatography techniques | Sus scrofa |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.22.1 | gastric mucosa | multiple isoforms | Sus scrofa | - |
| 3.1.22.1 | liver | multiple isoforms | Sus scrofa | - |
| 3.1.22.1 | spleen | multiple isoforms | Sus scrofa | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.22.1 | DNA + H2O | - |
Sus scrofa | oligonucleotides + ? | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.1.22.1 | dimer | alphabeta, 1 * 35000 + 1 * 10000, SDS-PAGE, gel filtration | Sus scrofa |
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