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Literature summary extracted from

  • Sjoestroem, J.E.; Loefdahl, S.; Philipson, L.
    Biological characteristics of a type I restriction-modification system in Staphylococcus aureus (1978), J. Bacteriol., 133, 1144-1149.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.21.3 S-adenosyl-L-methionine
-
Escherichia coli
3.1.21.3 S-adenosyl-L-methionine required Staphylococcus aureus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.21.3 Mg2+ required Staphylococcus aureus
3.1.21.3 Mg2+ required Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.21.3 additional information Escherichia coli
-
?
-
?
3.1.21.3 additional information Staphylococcus aureus restricts unmodified phage DNA after both infection and transfection ?
-
?
3.1.21.3 additional information Staphylococcus aureus RN450 restricts unmodified phage DNA after both infection and transfection ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.1.21.3 Citrobacter freundii
-
enzyme CfrAI
-
3.1.21.3 Escherichia coli
-
enzyme sEcoAI, EcoBI, EcoDI, EcoDXXI, EcoEI, EcoKI, EcoR124I and enzyme EcoR124/3I
-
3.1.21.3 Staphylococcus aureus
-
-
-
3.1.21.3 Staphylococcus aureus RN450
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.21.3 duplex DNA + ATP
-
Escherichia coli double-stranded DNA fragments with terminal 5'-phosphate + ADP + inorganic phosphate
-
?
3.1.21.3 duplex DNA + ATP
-
Citrobacter freundii double-stranded DNA fragments with terminal 5'-phosphate + ADP + inorganic phosphate
-
?
3.1.21.3 duplex DNA + ATP restricts unmodified phage DNA Staphylococcus aureus double-stranded DNA fragments with terminal 5'-phosphate + ADP + inorganic phosphate
-
?
3.1.21.3 duplex DNA + ATP restricts unmodified phage DNA Staphylococcus aureus RN450 double-stranded DNA fragments with terminal 5'-phosphate + ADP + inorganic phosphate
-
?
3.1.21.3 additional information
-
Escherichia coli ?
-
?
3.1.21.3 additional information restricts unmodified phage DNA after both infection and transfection Staphylococcus aureus ?
-
?
3.1.21.3 additional information restricts unmodified phage DNA after both infection and transfection Staphylococcus aureus RN450 ?
-
?

Synonyms

EC Number Synonyms Comment Organism
3.1.21.3 CfrAI
-
Citrobacter freundii
3.1.21.3 EcoAI
-
Escherichia coli
3.1.21.3 EcoBI
-
Escherichia coli
3.1.21.3 EcoDI
-
Escherichia coli
3.1.21.3 EcoDXXI
-
Escherichia coli
3.1.21.3 EcoEI
-
Escherichia coli
3.1.21.3 EcoKI
-
Escherichia coli
3.1.21.3 EcoR124/3I
-
Escherichia coli
3.1.21.3 EcoR124I
-
Escherichia coli

Cofactor

EC Number Cofactor Comment Organism Structure
3.1.21.3 ATP required Staphylococcus aureus
3.1.21.3 ATP required Escherichia coli
3.1.21.3 ATP is degraded during reaction Staphylococcus aureus
3.1.21.3 ATP is degraded during reaction Escherichia coli