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Literature summary extracted from

  • Kondo, K.; Toda, H.; Narita, K.
    Characterisation of phospholipase A activity of b 1-Bungarotoxin from Bungarus multicinctus venom (1978), J. Biochem., 84, 1291-1300.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.1.4 deoxycholate prevents p-bromophenacyl bromide inactivation Bungarus multicinctus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.4 p-bromophenacyl bromide
-
 Bungarus multicinctus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.1.4 Ca2+
-
 Crotalus adamanteus
3.1.1.4 Ca2+ prevents p-bromophenacyl bromide inactivation Bungarus multicinctus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.4 phospholipids + H2O Bungarus multicinctus presynaptic neurotoxicity of neutral PLA2 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.4 Bungarus multicinctus
-
-
-
3.1.1.4 Crotalus adamanteus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.1.4
-
 Bungarus multicinctus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.4 venom
-
 Crotalus adamanteus
-
3.1.1.4 venom
-
 Bungarus multicinctus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.1.4 5.9
-
 substrate: phosphatidylcholine Bungarus multicinctus
3.1.1.4 12.6
-
 substrate: phosphatidylcholine Crotalus adamanteus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.4 phosphatidylcholine + H2O
-
 Crotalus adamanteus 1-acylglycerophosphocholine + fatty acid
-
 ?
3.1.1.4 phosphatidylcholine + H2O
-
 Bungarus multicinctus 1-acylglycerophosphocholine + fatty acid
-
 ?
3.1.1.4 phospholipids + H2O presynaptic neurotoxicity of neutral PLA2 Bungarus multicinctus ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.1.4 8
-
 substrate: dispersed phosphatidylcholine Bungarus multicinctus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.1.1.4 6 9
-
 Bungarus multicinctus

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
3.1.1.4 2 8 full activity after 20 h at 37°C in acidic medium Bungarus multicinctus