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Literature summary extracted from

  • Feaster, S.R.; Quinn, D.M.
    Mechanism-based inhibitors of mammalian cholesterol esterase (1997), Methods Enzymol., 286, 231-252.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.1.13 Trihydroxy bile salts
-
 Sus scrofa
3.1.1.13 Trihydroxy bile salts
-
 Rattus sp.

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.13 2-(5,6,7,8)-tetrahydronaphthyl-N-hexyl carbamate biphasic inhibition time-course Rattus sp.
3.1.1.13 haloketones
-
 Sus scrofa
3.1.1.13 hexylboronic acids
-
 Sus scrofa
3.1.1.13 phenyl-n-butylboronic acid tight-binding competetive inhibitor Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.13 cholesteryl esters + H2O Sus scrofa important role in fat digestion in infants cholesterol + fatty acid
-
 r
3.1.1.13 cholesteryl esters + H2O Rattus sp. important role in fat digestion in infants cholesterol + fatty acid
-
 r

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.13 Rattus sp.
-
-
-
3.1.1.13 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.13 pancreas
-
 Sus scrofa
-
3.1.1.13 pancreas
-
 Rattus sp.
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.13 cholesteryl esters + H2O important role in fat digestion in infants Sus scrofa cholesterol + fatty acid
-
 r
3.1.1.13 cholesteryl esters + H2O important role in fat digestion in infants Rattus sp. cholesterol + fatty acid
-
 r
3.1.1.13 p-nitrophenyl butyrate + H2O
-
 Sus scrofa p-nitrophenol + butanoic acid
-
 r
3.1.1.13 p-nitrophenyl butyrate + H2O
-
 Rattus sp. p-nitrophenol + butanoic acid
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.1.13 CEase
-
 Sus scrofa
3.1.1.13 CEase
-
 Rattus sp.