Literature summary extracted from

Saxild, H.H.; Nygaard, P.
Gene-enzyme relationships of the purine biosynthetic pathway in Bacillus subtilis (1988), Mol. Gen. Genet., 211, 160-167.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
4.1.1.21	-	Bacillus subtilis
6.3.3.1	expression in Escherichia coli	Bacillus subtilis

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
4.1.1.21	1-(5-Phosphoribosyl)-5-aminoimidazole + CO2	Bacillus subtilis	enzyme of the de novo purine biosynthesis	?	-	?
6.3.3.1	ATP + 2-(formamido)-N1-(5-phosphoribosyl)acetamidine	Bacillus subtilis	enzyme of purine biosynthetic pathway	?	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.1.1.21	Bacillus subtilis	-	-	-
6.3.3.1	Bacillus subtilis	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.1.1.21	1-(5-Phosphoribosyl)-5-aminoimidazole + CO2	-	Bacillus subtilis	1-(5-Phosphoribosyl)-5-amino-4-imidazolecarboxylate	-	?
4.1.1.21	1-(5-Phosphoribosyl)-5-aminoimidazole + CO2	enzyme of the de novo purine biosynthesis	Bacillus subtilis	?	-	?
6.3.3.1	ATP + 2-(formamido)-N1-(5-phosphoribosyl)acetamidine	-	Bacillus subtilis	ADP + phosphate + 1-(5-phosphoribosyl)-5-aminoimidazole	-	?
6.3.3.1	ATP + 2-(formamido)-N1-(5-phosphoribosyl)acetamidine	enzyme of purine biosynthetic pathway	Bacillus subtilis	?	-	?

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Release 2023.1 (January 2023)