EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
6.3.2.6 | Co2+ | can replace Mg2+, maximal activation at 0.04 mM | Gallus gallus | |
6.3.2.6 | Mg2+ | at 0.05 mM ADP, Mg2+ saturation is reached at 2-3 mM | Gallus gallus | |
6.3.2.6 | Mn2+ | can replace Mg2+, maximal activation at 0.06 mM | Gallus gallus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.3.2.6 | ATP + 1-(5'-phosphoribosyl)-5-amino-4-carboxyimidazole + L-Asp | Gallus gallus | one of the enzymes of the series involved in the biosynthesis of the purine nucleotides de novo | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.3.2.6 | Gallus gallus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
6.3.2.6 | - |
Gallus gallus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
6.3.2.6 | liver | - |
Gallus gallus | - |
EC Number | Storage Stability | Organism |
---|---|---|
6.3.2.6 | -20°C, concentrated enzyme, above 1 mg/ml, stable | Gallus gallus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.3.2.6 | ATP + 1-(5'-phosphoribosyl)-5-amino-4-carboxyimidazole + L-Asp | r | Gallus gallus | ADP + phosphate + 1-(5'-phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole | - |
? | |
6.3.2.6 | ATP + 1-(5'-phosphoribosyl)-5-amino-4-carboxyimidazole + L-Asp | in the reverse reaction phosphate can be replaced by arsenate | Gallus gallus | ADP + phosphate + 1-(5'-phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole | - |
? | |
6.3.2.6 | ATP + 1-(5'-phosphoribosyl)-5-amino-4-carboxyimidazole + L-Asp | in the reverse reaction ADP cannot be replaced by any of the other nucleoside diphosphates | Gallus gallus | ADP + phosphate + 1-(5'-phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole | - |
? | |
6.3.2.6 | ATP + 1-(5'-phosphoribosyl)-5-amino-4-carboxyimidazole + L-Asp | one of the enzymes of the series involved in the biosynthesis of the purine nucleotides de novo | Gallus gallus | ? | - |
? |