Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Lacoste, A.M.; Poulsen, M.; Cassaigne, A.; Neuzil, E.
    Inhibition of D-alanyl-D-alanine ligase in different bacterial species by amino phosphonic acids (1979), Curr. Microbiol., 2, 113-117.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.3.2.4 2-aminoethylphosphonate weak Pseudomonas aeruginosa
6.3.2.4 D-(1-Aminoethyl)phosphonic acid DL- Pseudomonas aeruginosa
6.3.2.4 D-cycloserine
-
 Pseudomonas aeruginosa
6.3.2.4 D-cycloserine
-
 Staphylococcus aureus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.3.2.4 additional information
-
 additional information
-
 Staphylococcus aureus
6.3.2.4 additional information
-
 additional information
-
 Pseudomonas aeruginosa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.3.2.4 ATP + Ala + Ala Staphylococcus aureus one step in peptidoglycan synthesis: the formation of D-Ala-D-Ala, the terminal dipeptide of the UDP-N-acetylmuramylpentapeptide ?
-
 ?
6.3.2.4 ATP + Ala + Ala Pseudomonas aeruginosa one step in peptidoglycan synthesis: the formation of D-Ala-D-Ala, the terminal dipeptide of the UDP-N-acetylmuramylpentapeptide ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.3.2.4 Pseudomonas aeruginosa
-
-
-
6.3.2.4 Staphylococcus aureus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.2.4 ATP + Ala + Ala one step in peptidoglycan synthesis: the formation of D-Ala-D-Ala, the terminal dipeptide of the UDP-N-acetylmuramylpentapeptide Staphylococcus aureus ?
-
 ?
6.3.2.4 ATP + Ala + Ala one step in peptidoglycan synthesis: the formation of D-Ala-D-Ala, the terminal dipeptide of the UDP-N-acetylmuramylpentapeptide Pseudomonas aeruginosa ?
-
 ?
6.3.2.4 ATP + D-Ala + D-Ala
-
 Staphylococcus aureus ADP + phosphate + D-Ala-D-Ala
-
 ?
6.3.2.4 ATP + D-Ala + D-Ala
-
 Pseudomonas aeruginosa ADP + phosphate + D-Ala-D-Ala
-
 ?