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Literature summary extracted from

  • Brown, G.M.
    Dihydrofolate synthetase (1971), Methods Enzymol., 18B, 771-775.
No PubMed abstract available

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
6.3.2.12 K+ monovalent cation requirement is satisfied by K+ or NH4+ Escherichia coli
6.3.2.12 Mg2+ required Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
6.3.2.12 Escherichia coli
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.3.2.12
-
Escherichia coli

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
6.3.2.12 additional information
-
-
Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.2.12 ATP + 7,8-dihydropteroate + L-Glu
-
Escherichia coli ADP + phosphate + 7,8-dihydrofolate
-
?
6.3.2.12 GTP + 7,8-dihydropteroate + L-Glu 35% of the activity relative to ATP Escherichia coli GDP + phosphate + 7,8-dihydrofolate
-
?
6.3.2.12 ITP + 7,8-dihydropteroate + L-Glu at 60% of the activity relative to ATP Escherichia coli IDP + phosphate + 7,8-dihydrofolate
-
?