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Literature summary extracted from
- A simple radioassay for dihydrofolate synthetase activity in Escherichia coli and its application to an inhibition study of new pteroate analogs (1980), Methods Enzymol., 66, 576-581.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 6.3.2.12 | analysis | a simple radioassay for dihydrofolate synthetase activity and its application to an inhibition study of new pteroate analogs | Escherichia coli |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 6.3.2.12 | Dihydro-10-thiopteroic acid | - |
Escherichia coli |  |
| 6.3.2.12 | dihydrofolic acid | - |
Escherichia coli | |
| 6.3.2.12 | dihydrohomopteroic acid | - |
Escherichia coli | |
| 6.3.2.12 | Dihydroisopteroic acid | - |
Escherichia coli | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 6.3.2.12 | Escherichia coli | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 6.3.2.12 | ATP + 7,8-dihydropteroate + L-Glu | - |
Escherichia coli | ADP + phosphate + 7,8-dihydrofolate | - |
? | |
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