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Literature summary extracted from

  • Pongsamart, S.; Ho, R.I.; Corman, L.; Foye, W.O.
    Inhibition of dihydrofolate synthetase from Neisseria gonorrhoeae by dihydropteroate and dihydrofolate derivatives (1981), Chem. Biol. Interact., 36, 369-373.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.3.2.12 Dihydro-10-carbonylfolic acid
-
 Neisseria gonorrhoeae
6.3.2.12 Dihydro-10-carbonylpteroic acid
-
 Neisseria gonorrhoeae
6.3.2.12 Dihydro-10-thiofolic acid
-
 Neisseria gonorrhoeae
6.3.2.12 Dihydro-10-thiopteroic acid
-
 Neisseria gonorrhoeae
6.3.2.12 Dihydrofolate derivatives
-
 Neisseria gonorrhoeae
6.3.2.12 dihydrofolic acid
-
 Neisseria gonorrhoeae
6.3.2.12 dihydrohomopteroic acid
-
 Neisseria gonorrhoeae
6.3.2.12 Dihydroisopteroic acid
-
 Neisseria gonorrhoeae
6.3.2.12 Dihydropteroate derivatives
-
 Neisseria gonorrhoeae

Organism

EC Number Organism UniProt Comment Textmining
6.3.2.12 Neisseria gonorrhoeae
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.2.12 ATP + 7,8-dihydropteroate + L-Glu
-
 Neisseria gonorrhoeae ADP + phosphate + 7,8-dihydrofolate
-
 ?