Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Narkiewicz, J.; Lapinska-Szumczyk, S.; Zurawa-Janicka, D.; Skorko-Glonek, J.; Emerich, J.; Lipinska, B.
    Expression of human HtrA1, HtrA2, HtrA3 and TGF-beta1 genes in primary endometrial cancer (2009), Oncol. Rep., 21, 1529-1537.
    View publication on PubMed

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.21.107 50000
-
 SDS-PAGE Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.107 Homo sapiens
-
-
-
3.4.21.108 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.107 endometrial cancer cell
-
 Homo sapiens
-
3.4.21.107 primary cell
-
 Homo sapiens
-
3.4.21.108 endometrioma cell
-
 Homo sapiens
-

Synonyms

EC Number Synonyms Comment Organism
3.4.21.107 HtrA1
-
 Homo sapiens
3.4.21.108 HtrA2
-
 Homo sapiens

Expression

EC Number Organism Comment Expression
3.4.21.107 Homo sapiens HtrA1 mRNA and protein levels are significantly decreased in endometrial cancer compared to normal tissues down
3.4.21.108 Homo sapiens 124 endometrial tissue specimens including 88 cancers and 36 normal endometria are analyzed. HtrA2 protein levels are significantly lower in endometrial cancer cells compared to normal cells down

General Information

EC Number General Information Comment Organism
3.4.21.107 physiological function HtrA1 is involved in the inhibition of tumor growth factor-beta signaling in endometrial tissues Homo sapiens