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Literature summary extracted from

  • Kawamoto, Y.; Ito, H.; Kobayashi, Y.; Suzuki, Y.; Akiguchi, I.; Fujimura, H.; Sakoda, S.; Kusaka, H.; Hirano, A.; Takahashi, R.
    HtrA2/Omi-immunoreactive intraneuronal inclusions in the anterior horn of patients with sporadic and SOD1 mutant amyotrophic lateral sclerosis (2010), Neuropathol. Appl. Neurobiol., 36, 331-344.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.4.21.108 medicine HtrA2/Omi is associated with the pathogenesis of amyotrophic lateral sclerosis Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.21.108 mitochondrion
-
 Homo sapiens 5739
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.21.108 36000
-
 Western blot, mature form Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.108 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.108 anterior horn
-
 Homo sapiens
-
3.4.21.108 spinal cord
-
 Homo sapiens
-

Synonyms

EC Number Synonyms Comment Organism
3.4.21.108 HtrA2/Omi
-
 Homo sapiens

General Information

EC Number General Information Comment Organism
3.4.21.108 physiological function it is analyzed whether abnormal expression of HtrA2/Omi occurs in amyotrophic lateral sclerosis patients: abnormal accumulations of HtrA2/Omi may occur in several types of motor neuronal inclusions in the anterior horn from sporadic amyotrophic lateral sclerosis and Cu/Zn superoxide dismutase (SOD1)-related familial amyotrophic lateral sclerosis (FALS) cases, and that HtrA2/Omi may be associated with the pathogenesis of both types of amyotrophic lateral sclerosis Homo sapiens