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Literature summary extracted from

  • Karsten, W.E.; Cook, P.F.
    Detection of a gem-diamine and a stable quinonoid intermediate in the reaction catalyzed by serine-glyoxylate aminotransferase from Hyphomicrobium methylovorum (2009), Biochim. Biophys. Acta, 1790, 575-580.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.6.1.45
-
 Hyphomicrobium methylovorum

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.6.1.45 D-serine competitive inhibition with L-serine Hyphomicrobium methylovorum

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.6.1.45 43880
-
 calculated from amino acid sequence Hyphomicrobium methylovorum

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.45 Hyphomicrobium methylovorum
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.6.1.45 Ni-NTA column chromatography Hyphomicrobium methylovorum

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.45 L-serine + glyoxylate
-
 Hyphomicrobium methylovorum 3-hydroxypyruvate + glycine
-
 r

Subunits

EC Number Subunits Comment Organism
2.6.1.45 homotetramer
-
 Hyphomicrobium methylovorum

Synonyms

EC Number Synonyms Comment Organism
2.6.1.45 serine-glyoxylate aminotransferase
-
 Hyphomicrobium methylovorum
2.6.1.45 SGAT
-
 Hyphomicrobium methylovorum

Cofactor

EC Number Cofactor Comment Organism Structure
2.6.1.45 pyridoxal 5'-phosphate contains 1 mol of pyridoxal 5'-phosphate per subunit Hyphomicrobium methylovorum

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.6.1.45 1.4
-
 D-serine
-
 Hyphomicrobium methylovorum