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Literature summary extracted from

  • Inagaki, R.; Tagawa, K.; Qi, M.L.; Enokido, Y.; Ito, H.; Tamura, T.; Shimizu, S.; Oyanagi, K.; Arai, N.; Kanazawa, I.; Wanker, E.E.; Okazawa, H.
    Omi /HtrA2 is relevant to the selective vulnerability of striatal neurons in Huntingtons disease (2008), Eur. J. Neurosci., 28, 30-40.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.4.21.108 medicine the function of Omi/HtrA2 is linked to selective vulnerability of striatal neurons in Huntingtons disease Homo sapiens
3.4.21.108 medicine the function of Omi/HtrA2 is linked to selective vulnerability of striatal neurons in Huntingtons disease Mus musculus
3.4.21.108 medicine the function of Omi/HtrA2 is linked to selective vulnerability of striatal neurons in Huntingtons disease Rattus norvegicus

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.21.108 into the pCR-Blunt vector and subsequently into the pAxCAwt cosmid for transfection Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.21.108 Omi siRNA
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.21.108 mitochondrial intermembrane space
-
 Homo sapiens 5758
-
3.4.21.108 mitochondrial intermembrane space
-
 Mus musculus 5758
-
3.4.21.108 mitochondrial intermembrane space
-
 Rattus norvegicus 5758
-
3.4.21.108 mitochondrion
-
 Homo sapiens 5739
-
3.4.21.108 mitochondrion
-
 Mus musculus 5739
-
3.4.21.108 mitochondrion
-
 Rattus norvegicus 5739
-

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.108 Homo sapiens
-
-
-
3.4.21.108 Mus musculus
-
-
-
3.4.21.108 Rattus norvegicus
-
 Wistar rat
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.108 brain
-
 Homo sapiens
-
3.4.21.108 brain
-
 Mus musculus
-
3.4.21.108 cerebral cortex
-
 Rattus norvegicus
-
3.4.21.108 embryo
-
 Rattus norvegicus
-
3.4.21.108 neuron striatal neuron Homo sapiens
-
3.4.21.108 neuron striatal neuron Mus musculus
-
3.4.21.108 neuron striatal neuron Rattus norvegicus
-

Synonyms

EC Number Synonyms Comment Organism
3.4.21.108 Omi/HtrA2
-
 Homo sapiens
3.4.21.108 Omi/HtrA2
-
 Mus musculus
3.4.21.108 Omi/HtrA2
-
 Rattus norvegicus