Literature summary extracted from
Raveendran, N.N.; Silver, K.; Freeman, L.C.; Narvaez, D.; Weng, K.; Ganta, S.; Lillich, J.D.
Drug-induced alterations to gene and protein expression in intestinal epithelial cell 6 cells suggest a role for calpains in the gastrointestinal toxicity of nonsteroidal anti-inflammatory agents (2008), J. Pharmacol. Exp. Ther., 325, 389-399.
Organism
| EC Number |
Organism |
UniProt |
Comment |
Textmining |
|---|
| 3.4.22.B28 |
Rattus norvegicus |
- |
- |
- |
Source Tissue
| EC Number |
Source Tissue |
Comment |
Organism |
Textmining |
|---|
| 3.4.22.B28 |
IEC-6 cell |
NS-398 decreases the expression of mRNA for calpain 8. Both NS-398 and indomethacin, but not SC-560, decrease the protein expression of calpains 8 |
Rattus norvegicus |
- |