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Literature summary extracted from

  • Srinivasula, S.M.; Gupta, S.; Datta, P.; Zhang, Z.; Hegde, R.; Cheong, N.; Fernandes-Alnemri, T.; Alnemri, E.S.
    Inhibitor of apoptosis proteins are substrates for the mitochondrial serine protease Omi/HtrA2 (2003), J. Biol. Chem., 278, 31469-31472.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.21.108 mitochondrion mature protein is released form the mitochondria into the cytosol during aopotosis Homo sapiens 5739
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Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.108 additional information Homo sapiens can promote caspase activation and cell death apoptosis ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.108 Homo sapiens
-
-
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.108 293 cell
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Homo sapiens
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.108 beta-casein + H2O
-
Homo sapiens ?
-
?
3.4.21.108 additional information Omi can degrade inhibitor of apoptosis proteins Homo sapiens ?
-
?
3.4.21.108 additional information can promote caspase activation and cell death apoptosis Homo sapiens ?
-
?

Synonyms

EC Number Synonyms Comment Organism
3.4.21.108 Omi
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Homo sapiens