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Literature summary extracted from

  • Phillips, M.I.; Davies, D.R.
    The mechanism of guanosine triphosphate depletion in the liver after a fructose load. The role of fructokinase (1985), Biochem. J., 228, 667-671.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.3 ADP
-
 Rattus norvegicus
2.7.1.3 GDP
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.1.3 0.56
-
 D-fructose pH 7.4, cosubstrate GTP Rattus norvegicus
2.7.1.3 0.83
-
 D-fructose pH 7.4, + ATP Rattus norvegicus
2.7.1.3 1.43
-
 ATP pH 7.4 Rattus norvegicus
2.7.1.3 1.53
-
 GTP pH 7.4 Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.3 ATP + D-fructose Rattus norvegicus
-
 ADP + D-fructose 1-phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.3 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.1.3
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.3 liver
-
 Rattus norvegicus
-

Storage Stability

EC Number Storage Stability Organism
2.7.1.3 -20°C, stable for several months Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.3 ATP + D-fructose
-
 Rattus norvegicus ADP + D-fructose 1-phosphate
-
 ?
2.7.1.3 GTP + D-fructose
-
 Rattus norvegicus ?
-
 ?