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Literature summary for 7.6.2.6 extracted from

  • Mackenzie, S.M.; Brooker, M.R.; Gill, T.R.; Cox, G.B.; Howells, A.J.; Ewart, G.D.
    Mutations in the white gene of Drosophila melanogaster affecting ABC transporters that determine eye colouration (1999), Biochim. Biophys. Acta, 1419, 173-185.
    View publication on PubMed
Search for more literature for 7.6.2.6

Protein Variants

Protein Variants Comment Organism
F590G major decrease in red eye color pigments, guanine transport affected Drosophila melanogaster
G243S major decrease in red and brown eye color pigments, guanine and tryptophan transport affected Drosophila melanogaster
G589E major decrease in red eye color pigments, guanine transport affected Drosophila melanogaster
H298N major decrease in red and brown eye color pigments, guanine and tryptophan transport affected Drosophila melanogaster

Localization

Localization Comment Organism GeneOntology No. Textmining
integral to membrane integral, protein products encoded by the white and brown genes Drosophila melanogaster
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + guanine/out Drosophila melanogaster
-
 ADP + phosphate + guanine/in
-
 ?
ATP + H2O + tryptophan/out Drosophila melanogaster
-
 ADP + phosphate + tryptophan/in
-
 ?

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + guanine/out
-
 Drosophila melanogaster ADP + phosphate + guanine/in
-
 ?
ATP + H2O + tryptophan/out
-
 Drosophila melanogaster ADP + phosphate + tryptophan/in
-
 ?

Subunits

Subunits Comment Organism
More ABC-transporter Drosophila melanogaster