Literature summary for 7.6.2.3 extracted from

Lu, Y.; Li, Z.; Rea, P.
AtMRP1 gene of Arabidopsis encodes a glutathione S-conjugate pump Isolation and functional definition of a plant ATP-binding cassette transporter gene (1997), Proc. Natl. Acad. Sci. USA, 94, 8243-8248 .

Search for more literature for 7.6.2.3

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Saccharomyces cerevisiae ycf1DELTA mutants	Arabidopsis thaliana

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
vacuolar membrane	-	Arabidopsis thaliana	5774	-

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Mg2+	required in form of Mg2+-ATP	Arabidopsis thaliana

Organism

Organism	UniProt	Comment	Textmining
Arabidopsis thaliana	Q9C8G9	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + H2O + glutathione disulfide[side 1]	-	Arabidopsis thaliana	ADP + phosphate + glutathione disulfide[side 2]	-	?
ATP + H2O + S-(2,4-dinitrophenyl)glutathione[side 1]	-	Arabidopsis thaliana	ADP + phosphate + S-(2,4-dinitrophenyl)glutathione[side 2]	-	?
ATP + H2O + S-(cyanidin-3-glucosidyl)glutathione[side 1]	highest activity	Arabidopsis thaliana	ADP + phosphate + S-(cyanidin-3-glucosidyl)glutathione[side 2]	-	?
ATP + H2O + S-(metolachlor)glutathione[side 1]	-	Arabidopsis thaliana	ADP + phosphate + S-(metolachlor)glutathione[side 2]	-	?

Synonyms

Synonyms	Comment	Organism
glutathione S-conjugate pump	-	Arabidopsis thaliana
MRP1	-	Arabidopsis thaliana
multidrug resistance-associated protein 1	-	Arabidopsis thaliana

General Information

General Information	Comment	Organism
metabolism	the enzyme transports glutathione S-conjugates of xenobiotics and endogenous substances, including herbicides and anthocyanins out of the cytosol	Arabidopsis thaliana

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Release 2023.1 (January 2023)